B-cell leukemia/lymphoma panel is a blood test that looks for certain proteins on the surface of white blood cells called B-lymphocytes. The proteins serve as markers that may be helpful in diagnosing leukemia or lymphoma.
A blood sample is needed.
The blood sample is sent to a laboratory, where a specialist checks the cell type and characteristics. This procedure is called immunophenotyping. The test is usually done using a technique called flow cytometry.
No special preparation is usually necessary.
When the needle is inserted to draw blood, some persons feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away.
This test may be done for the following reasons:
Veins and arteries vary in size from one patient to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.
Other risks associated with having blood drawn are slight, but may include:
B lymphocyte cell surface markers
Czuchlewski DR, Viswanatha DS, Larson RS. Molecular diagnosis of hematopoietic neoplasms. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 22nd ed. Philadelphia, Pa: Elsevier Saunders; 2011:chap 75.
Updated by: Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.
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