The gastrin blood test measures the amount of the hormone gastrin in blood.
A blood sample is needed.
Certain medicines may affect the results of this test. Your doctor will tell you if you need to stop taking any medicines. Do not stop taking any medicine before talking to your doctor.
Medicines that can increase gastrin measurements include antacids, H2-blocking agents (such as cimetidine), and proton pump inhibitors (such as omeprazole).
When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging sensation. Afterward, there may be some throbbing or a slight bruise. These soon go away.
Gastrin is the main hormone that controls the release of acid in your stomach. When there is food in the stomach, gastrin is released into the blood. As the acid level rises in your stomach and intestines, your body normally makes less gastrin.
Your doctor may order this test if you have signs or symptoms of a problem linked to an abnormal amount of gastrin. This includes peptic ulcer disease.
Normal values are generally less than 100 pg/mL.Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your doctor about the meaning of your specific test result.
Too much gastrin causes severe peptic ulcer disease. A higher than normal level may also be due to:
Veins and arteries vary in size from one patient to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.
Other risks associated with having blood drawn are slight but may include:
Salwen MJ, Siddiqi HA, Gress FG, Bowne WB. Laboratory diagnosis of gastrointestinal and pancreatic disorders. In: McPherson RA, Pincus MR, eds. Henry’s Clinical Diagnosis and Management by Laboratory Methods. 22nd ed. Philadelphia, Pa: Elsevier Saunders; 2011:chap 22.
Updated by: Brent Wisse, MD, Associate Professor of Medicine, Division of Metabolism, Endocrinology & Nutrition, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Bethanne Black, and the A.D.A.M. Editorial team.
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