Smear of duodenal fluid aspirate is an exam of fluid from the duodenum to check for signs of an infection (such as giardia or strongyloides). Rarely, this test is also done in a newborn to check for biliary atresia.
A sample is taken during a procedure called an esophagogastroduodenoscopy (EGD).
Do not eat or drink anything for 12 hours before the test.
You may feel like you have to gag as the tube is passed, but the procedure is usually not painful. You can get medicines to help you relax and be free of pain. If you get anesthesia, you cannot drive for the rest of the day.
The test is done to look for infection of the small bowel. However, it is not often needed. In most cases, this test is only done when a diagnosis cannot be made with other tests.
There should be no disease-causing organisms in the duodenum. Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
The results may show the presence of giardia protozoa, the intestinal parasite strongyloides, or another infectious organism.
The risks of this test include:
Some people may not be able to have this test because of other medical conditions.
Other tests that are less invasive can often find the source of the infection.
Duodenal aspirated fluid smear
DuPont HL. Approach to the patient with suspected enteric infection. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 291.
Semrad CE. Approach to the patient with diarrhea and malabsorption. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 142.
Giannella RA. Infectious enteritis and proctocolitis and bacterial food poisoning. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger& Fordtran’s Gastrointestinal and Liver Disease. 9th ed. Philadelphia, PA: Saunders Elsevier; 2010:chap 107.
Croft AC, Woods GL. Specimen collection and handling for diagnosis of infectious diseases. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 22nd ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 63.
Salwen MJ, Siddiqi HA, Gress FG, Bowne WB. Laboratory diagnosis of gastrointestinal and pancreatic disorders. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 22nd ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 22.
Fritsche TR, Selvarangan R. Medical parasitology. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 22nd ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 62.
Updated by: Jenifer K. Lehrer, MD, Department of Gastroenterology, Frankford-Torresdale Hospital, Aria Health System, Philadelphia, PA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 1997-2015, A.D.A.M., Inc. Duplication for commercial use must be authorized in writing by ADAM Health Solutions.