Diabetes insipidus (DI) causes frequent urination. You become extremely thirsty, so you drink. Then you urinate. This cycle can keep you from sleeping or even make you wet the bed. Your body produces lots of urine that is almost all water.
DI is different from diabetes mellitus (DM), which involves insulin problems and high blood sugar. The symptoms can be similar. However, DI is related to how your kidneys handle fluids. It's much less common than DM. Urine and blood tests can show which one you have.
Usually, DI is caused by a problem with your pituitary gland or your kidneys. Treatment depends on the cause of the problem. Medicines can often help.
NIH: National Institute of Diabetes and Digestive and Kidney Diseases
- ClinicalTrials.gov: Diabetes Insipidus (National Institutes of Health)
- Genetics Home Reference: Nephrogenic diabetes insipidus (National Library of Medicine)
- Genetics Home Reference: Neurohypophyseal diabetes insipidus (National Library of Medicine)
- Genetics Home Reference: Wolfram syndrome (National Library of Medicine)
Journal ArticlesReferences and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Early-onset central diabetes insipidus is associated with de novo arginine...
- Article: Abnormal plasma sodium concentrations in patients treated with desmopressin for...
- Article: A calcium-dependent protease as a potential therapeutic target for Wolfram...
- Diabetes Insipidus -- see more articles
- Diabetes Insipidus, Central (For Parents) (Nemours Foundation)
- Antidiuretic hormone blood test Available in Spanish
- Diabetes insipidus Available in Spanish
- Diabetes Insipidus (National Institute of Diabetes and Digestive and Kidney Diseases)
- Diabetes insipidus - central Available in Spanish
- Diabetes insipidus - nephrogenic Available in Spanish
- Urine 24-hour volume Available in Spanish
- Urine concentration test Available in Spanish