Metabolic syndrome is becoming very common in the United States. Doctors are not sure whether the syndrome is due to one single cause. But all of the risks for the syndrome are related to obesity.
The two most important risk factors for metabolic syndrome are:
Other risk factors include:
People who have metabolic syndrome often have one or more other factors that may be linked with the condition, including:
Metabolic syndrome is present if you have three or more of the following signs:
The goal of treatment is to reduce your risk of heart disease and diabetes.
Your doctor will recommend lifestyle changes or medicines:
Your doctor may recommend daily low-dose aspirin.
If you smoke, now is the time to quit.
People with metabolic syndrome have an increased long-term risk of developing heart disease, type 2 diabetes, stroke, kidney disease, and poor blood supply to the legs.
Call your health care provider if you have signs or symptoms of this condition.
Insulin resistance syndrome; Syndrome X
Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention: National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009;120:1640-1645.
Gallagher EJ, LeRoith D, Karnielli E. The metabolic syndrome--from insulin resistance to obesity and diabetes. Med Clin N Am. 2011;95:855-873.
Rosenzweig JL, Ferrannini E, Grundy SM, et al. Primary prevention of cardiovascular disease and type 2 diabetes in patients at metabolic risk: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2008; 93:3671-3689.
Updated by: Brent Wisse, MD, Associate Professor of Medicine, Division of Metabolism, Endocrinology & Nutrition, University of Washington School of Medicine, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.
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