National Institutes of Health
- The primary NIH organization for research on Skin Pigmentation Disorders is the National Institute of Arthritis and Musculoskeletal and Skin Diseases
Pigmentation means coloring. Skin pigmentation disorders affect the color of your skin. Skin cells give your skin color by making a substance called melanin. When these cells become damaged or unhealthy, it affects melanin production. Some pigmentation disorders affect just patches of skin. Others affect your entire body.
If your body makes too much melanin, your skin gets darker. Pregnancy, Addison's disease and sun exposure all can make your skin darker. If your body makes too little melanin, your skin gets lighter. Vitiligo is a condition that causes patches of light skin. Albinism is a genetic condition affecting all of a person's skin. Infections, blisters and burns can cause lighter skin.
References and abstracts from MEDLINE/PubMed (National Library of Medicine)