National Institutes of Health
- The primary NIH organization for research on Spinal Muscular Atrophy is the National Institute of Neurological Disorders and Stroke
Spinal muscular atrophy (SMA) is a genetic disease that attacks nerve cells, called motor neurons, in your spinal cord. These neurons communicate with your voluntary muscles - the ones you can control, like in your arms and legs. As you lose the neurons, your muscles weaken. This can affect walking, crawling, breathing, swallowing and head and neck control.
SMA runs in families. Parents usually have no symptoms, but still carry the gene. Genetic counseling is important if the disease runs in your family.
There are many types of SMA, and some of them are fatal. Life expectancy depends on the type you have and how it affects your breathing. There is no cure. Medicines and physical therapy help treat symptoms.
NIH: National Institute of Neurological Disorders and Stroke
References and abstracts from MEDLINE/PubMed (National Library of Medicine)