National Institutes of Health
- The primary NIH organization for research on Wegener's Granulomatosis is the National Institute of Allergy and Infectious Diseases
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National Institutes of Health
Wegener's Granulomatosis
Wegener's granulomatosis is a rare disease. It is a type of vasculitis, or inflammation of the blood vessels. The inflammation limits the flow of blood to important organs, causing damage. It can affect any organ, but it mainly affects the sinuses, nose, trachea (windpipe), lungs, and kidneys.
The cause of Wegener's granulomatosis is unknown. It can affect people at any age. Men and women are equally affected. It is more common in whites. Symptoms may include joint pain, weakness, tiredness, and cold symptoms such as a runny nose that doesn't get better. Doctors use blood tests, chest X-rays, and biopsies to diagnose the disease and rule out other causes of the symptoms.
Early treatment is important. Most people improve with medicines to slow or stop the inflammation.
NIH: National Institute of Allergy and Infectious Diseases
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Wegener's Granulomatosis(National Institute of Allergy and Infectious Diseases)
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Wegener's Granulomatosis
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Overviews
- Granulomatosis with Polyangiitis (Wegener's)(American College of Rheumatology)
- Wegener's Granulomatosis(Johns Hopkins Vasculitis Center)
- Wegener's Granulomatosis(Mayo Foundation for Medical Education and Research)
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Diagnosis/Symptoms
- ANCA / MPO / PR3 Antibodies(American Association for Clinical Chemistry)
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Treatment
- Cyclophosphamide (Cytoxan)(Johns Hopkins Vasculitis Center)
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Wegener's Granulomatosis: Treatment(National Institute of Arthritis and Musculoskeletal and Skin Diseases)
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Clinical Trials
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ClinicalTrials.gov: Wegener Granulomatosis(National Institutes of Health)
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ClinicalTrials.gov: Wegener Granulomatosis
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Journal Articles
References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Dysregulation of histone deacetylase and histone acetyltransferase in development of...
- Article: Clinical manifestations and treatment of idiopathic and Wegener granulomatosis-associated subglottic...
- Article: Scleritis--Wegener's granulomatosis.
- Wegener's Granulomatosis -- see more articles
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Organizations
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Patient Handouts
- Wegener's granulomatosis
- Also available in Spanish
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