September Release - 09/02/2014
This release of RxNorm is consistent with the 2014AA UMLS Metathesaurus release. For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm technical documentation.
Sources
The following sources have been updated since the previous RxNorm release:
| Source Name | SAB | Date Updated |
|---|---|---|
| Gold Standard Drug Database | GS | 08/01/2014 |
| Medi-Span Master Drug Data Base | MDDB | 07/30/2014 |
| Multum MediSource Lexicon | MMSL | 08/01/2014 |
| Micromedex RED BOOK | MMX | 08/04/2014 |
| FDA Structured Product Labels | MTHSPL | 08/25/2014 |
| FDB MedKnowledge (formerly NDDF Plus) | NDDF | 08/06/2014 |
| Veterans Health Administration National Drug File - Reference Terminology | NDFRT | 09/02/2014 |
| NDFRT FDASPL relationships | NDFRT_FDASPL | 09/02/2014 |
| NDFRT FMTSME relationships | NDFRT_FMTSME | 09/02/2014 |
| US Edition of SNOMED CT (drug information) | SNOMEDCT_US | 07/31/2014 |
| Veterans Health Administration National Drug File | VANDF | 07/17/2014 |
The following sources have not been updated in this release:
| Source Name | SAB | Date Updated |
|---|---|---|
| Anatomical Therapeutic Chemical Classification System | ATC | 2014 |
| Medical Subject Headings (MeSH) | MSH | 02/10/2014 |
| FDA National Drug Code Directory | MTHFDA | 06/01/2011 |
Data Changes
Prescribable Names:
This release includes another batch of prescribable names (TTY=PSN) for many drugs with topical dose forms, including some ointments, gels, and foams.
MTHSPL Active Moieties:
In addition to the data already available in RxNorm for the active and inactive ingredients for all structured product labels (SPLs) on DailyMed, RxNorm now includes the active moieties associated with the active ingredients in the DailyMed SPLs. The active moieties are treated in the same way as the active and inactive ingredients in RXNCONSO.RRF, receiving a term type (TTY) value of 'SU' (substance) and a CODE value of the Food and Drug Administration (FDA) unique ingredient identifier (UNII) code found in the SPL.
Along with the active moiety data comes some changes to the relationships between ingredients and drug products in the MTHSPL data. In previous releases, the relationship between active and inactive ingredients and drug products was 'has_ingredient / ingredient_of'. Each of the three types of ingredients will now have unique bidirectional relationships with associated drug products in the RXNREL.RRF file:
- has_active_ingredient / active_ingredient_of
- has_active_moiety / active_moiety_of
- has_inactive_ingredient / inactive_ingredient_of
RXNORM UNII_CODE Attribute:
RxNorm no longer includes the FDA UNII codes as 'UNII_CODE' attributes associated with SAB=RXNORM ingredients in the RXNSAT.RRF file. With the addition of active moiety UNII codes mentioned above, RxNorm now has a robust set of ingredient UNII codes for all drug products on DailyMed in the RXNCONSO.RRF file. You can find these in the CODE field for SAB=MTHSPL, TTY=SU rows.
NDFRT Drug Interactions:
The Veterans Health Administration (VHA) is no longer providing drug interaction concepts, attributes, and relationships in National Drug File - Reference Terminology (NDFRT). As a result, you will not find these data in the RxNorm release files or other RxNorm applications (RxNorm API, RxNav, and RxMix). The National Library of Medicine (NLM) is currently investigating alternative sources for drug interaction information for its applications.
Data Counts
| Term Type or Attribute | Number |
|---|---|
| Active GPCKs | 360 |
| Active BPCKs | 443 |
| Active SCDs | 19766 |
| Active SBDs | 10856 |
| Active RXNORM MINs | 3892 |
| Active RXNORM INs | 10109 |
| Active RXNORM PINs | 2345 |
| Active RXNORM BNs | 6740 |
| Active RXNORM DFs | 103 |
| Obsolete GPCKs | 120 |
| Obsolete BPCKs | 113 |
| Obsolete SCDs | 14599 |
| Obsolete SBDs | 10357 |
| Obsolete RXNORM MINs | 0 |
| Obsolete RXNORM INs | 0 |
| Obsolete RXNORM PINs | 0 |
| Obsolete RXNORM BNs | 9472 |
| Obsolete RXNORM DFs | 57 |
| Editor-suppressed SCDs | 1077 |
| Editor-suppressed SBDs | 947 |
| OCD atoms | 330317 |
| Source-asserted NDCs | 1310383 |
| Distinct source-asserted NDCs | 592115 |
| SAB=RXNORM NDCs | 200772 |
| Distinct SAB=RXNORM NDCs | 200772 |
Last Reviewed: September 2, 2014