2006 JANUARY–FEBRUARY;
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Technical Notes

New Clinical Advisory Issued
[Editor's Note Added January 06, 2006]
[Editor's Note Added January 09, 2006]

New Clinical Advisory Issued

January 04, 2006 [posted]
January 06, 2006 [editor's note added]
January 09, 2006 [editor's note added]

[Editor's Note: The National Cancer Institute (NCI) classified this announcement as an advisory not an alert.]

The National Cancer Institute (NCI) has issued a new Clinical Advisory on January 4, 2006:

The National Cancer Institute (NCI), part of the National Institutes of Health, today issued an announcement encouraging treatment with anticancer drugs via two methods, after surgery, for women with advanced ovarian cancer. The combined methods, which deliver drugs into a vein and directly into the abdomen, extend overall survival for women with advanced ovarian cancer by about a year.

The clinical announcement to surgeons and other medical professionals who treat women with ovarian cancer was made with the support of six professional societies and advocacy groups. The announcement coincides with publication in the New England Journal of Medicine* of the results of a large clinical trial by Deborah Armstrong, M.D., medical oncologist and an associate professor at Johns Hopkins Kimmel Cancer Center in Baltimore, Md., and her colleagues in an NCI-supported research network known as the Gynecologic Oncology Group (GOG). This is the eighth trial evaluating the use of chemotherapy delivered into the abdomen for ovarian cancer. Together, these trials show a significant improvement in survival for women with advanced ovarian cancer.

Links to Clinical Alerts/Advisories can also be found from these NLM Web sites:

*Armstrong DK, Bundy B, Wenzel L, Huang HQ, Baergen R, Lele S, Copeland LJ, Walker JL, Burger RA. Intraperitoneal cisplatin and paclitaxel in ovarian cancer. N Engl J Med. 2006 Jan 5;354(1):34-43. [Editor's Note: This citation is now available in PubMed (PMID: 16394300).]

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