About

Clem McDonald, MD
Senior Investigator, Office of the Director, NLMMy research centers on the comparison and analysis of DNA and protein sequences, with a recent focus on multiple alignments and the correlations among positions within protein superfamilies.
Contact Information
Building 38A, 8600 Rockville Pike MSC 6075 Bethesda, MD 20894
Tel: (301) 496-4441
Research Interests
His research focuses on electronic medical records (EMRs), their use in clinical care and research, the data standards needed to feed EMRs and epidemiological studies of the clinical databases. He is a member of the National Academy of Sciences, and has published more than 300 papers that have garnered 18 thousand citations. Prior to coming to NLM, Dr. McDonald served as the a distinguished Professor of Medicine and of Medical Informatics at the Indiana University School of Medicine and the Director of the Regenstrief Institute for Health Care, a privately endowed research institute tied to Indiana University. Dr. McDonald developed the Regenstrief Medical Record, one of the first electronic health record (EHR) systems, and introduced the first use of decision support in randomized trials of health information systems in a 1976 study (McDonald, 1976). He and his colleagues developed the first U.S. Health Information Exchange (HIE) which was the model for the many HIEs that followed, and which now carries 6 billion results from hospitals across Indiana. He developed the Logical Observation Identifier Names and Codes (LOINC) database to provide universal identifiers for clinical observations, was coauthor of the UCUM standard for computable units of measure, one of the founders and authors of the Health Level 7 (HL7) standard and a major contributor to the genomics reporting chapter of the 2018 V2 laboratory results message. He is active in the development of the FHIR genomics reporting standard, and FHIR input forms development (Questionnaire and Structured Data Capture) and has developed web-based software tools to generate executable web forms and clinical flowsheets.
Publications
Reminders to physicians from an introspective computer medical record: a two-year randomized trial
Physician inpatient order writing on microcomputer workstations: effects on resource utilization
A computerized reminder system to increase the use of preventive care for hospitalized patients