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National Library of Medicine Technical BulletinNational Library of Medicine Technical Bulletin

Table of Contents: 2021 JULY–AUGUST No. 441

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RxNorm July 2021 Release

RxNorm July 2021 Release. NLM Tech Bull. 2021 Jul-Aug;(441):b1.

2021 July 01 [posted]

The RxNorm July monthly release became available for download on Tuesday, July 6, 2021. It includes two new COVID-19-related clinical drug concepts. See below for more details. 


Two New COVID-19-Related Concepts Added

First, sotrovimab, a drug allowed under the U.S. Food & Drug Administration Emergency Use Authorization (EUA), became available in the RxNorm June 9, 2021 weekly release and is included in the RxNorm July 2021 monthly release.

Here is the sotrovimab Semantic Clinical Drug (SCD) name, RxNorm Concept Unique Identifier (RXCUI), and National Drug Code (NDC):

  • SCD: 8 ML sotrovimab 62.5 MG/ML Injection
  • RXCUI: 2550903
  • NDC: 00173090186

Second, a propofol lipid emulsion product was also added. This product is an investigational infusion to maintain sedation in patients 16 or older who require mechanical ventilation in an Intensive Care Unit (ICU) setting during the 2019 coronavirus disease (COVID-19) pandemic.

Here is the new propofol lipid emulsion Semantic Clinical Drug (SCD) name, RxNorm Concept Unique Identifier (RXCUI), and National Drug Code (NDC):

  • SCD: 100 ML propofol lipid emulsion 10 MG/ML Injection
  • RXCUI: 2559909
  • NDC: 00264485001

The COVID-19 Vaccines and Medications in RxNorm page lists all the COVID-19 related clinical drug products in RxNorm.


As a courtesy to users, this section provides advance notice of possible upcoming RxNorm data changes. More information about each change will be provided or repeated in the future. Please note that planned data changes and timelines may change if issues arise.

  • REMINDER: Basis of Strength (BoSS) Attributes Changing Fall 2021

Several BoSS attributes are planned to change this fall. A specific month is not available, but is likely to occur September 2021 at the earliest. Below are more details. Please plan accordingly.

  • BoSS Attributes Moving:
    • RXN_BOSS_AI, RXN_BOSS_AM, and RXN_BOSS_FROM attributes will change from being present on an SCDC to an SCD, likewise on an SBDC to an SBD
    • Please note that this change will initially affect many but not all relevant concepts. For example, some products, such as medical gases and multi-ingredient products including multivitamins, will be addressed at a later time.
  • BoSS Attribute Name Changes:
    • RXN_BOSS_AI will be renamed RXN_AI
    • RXN_BOSS_AM will be renamed RXN_AM
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