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Grants and Funding: Extramural Programs (EP)

NLM Express Research Grants in Biomedical Informatics (R01) (PAR-16-404) 


An application to NLM's research grant program should focus on a well-defined research problem and propose a rigorous research design, based on preliminary studies, which will result in innovations that advance what is known in the field of informatics and have the capacity to improve human health. NLM will not support infrastructure development or continued development of existing software tools or knowledge resources as an endpoint of research funded through this FOA, though such tools, data sets or other compilations of knowledge may be used to test ideas and methods. Applicants interested in building or sustaining tools and research resources should consider opportunities such as PA-14-155 "Early Stage Development of Technologies in Biomedical Computing, Informatics, and Big Data Science (R01)" or PAR-14-156 "Extended Development, Hardening and Dissemination of Technologies in Biomedical Computing, Informatics and Big Data Science (R01)".

Investigators whose budgetary needs are not met by this announcement can also apply through the NIH Parent R01 (PA-16-160), with a cover letter requesting assignment to NLM. Those who do so should use PAR-16-404 as a source of guidance about NLM's research grant priorities and scope of interest.

This program expires September 8, 2019 unless reissued. Only electronic applications are accepted.

NLM Contacts

Clinical and Public Health Informatics: Dr. Hua-Chuan Sim,
Bioinformatics and Translational Informatics: Dr. Jane Ye,
Consumer Health Informatics and Information Sciences: Dr. Alan VanBiervliet,


Deadlines for New Applications: February 5, June 5 and October 5 each year
Deadlines for Revised Applications: March 5, July 5 and November 5 each year
Full listing of deadlines for competing applications: