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Grants and Funding: Extramural Programs (EP)

New and Early Stage Investigators

A Program Director or Principal Investigator (PD/PI) is considered a New Investigator (NI) if he/she has not previously competed successfully as PD/PI for a significant NIH independent research award. An independent research award is considered to be a R01 or equivalent award. R21s, R03s or K awards do not impact your New Investigator status. An Early Stage Investigator (ESI) is a New Investigator within ten years of completing their terminal research degree or within ten years of completing their medical residency. The involvement of New Investigators is considered essential to the vitality of health-related research.

Applications from NI/ESIs will be given special consideration during peer review and at the time of funding. Peer reviewers will be instructed to focus more on the proposed approach than on the track record, and to expect less preliminary data than would be provided by an established investigator. Please refer to, under “Fundable Range”, to see the special provision NLM makes for R01 applications from NI/ESIs, regarding impact scores.

See // for more information about the NIH NI/ESI policies.

NLM NI/ESI Webinar

The NLM Division of Extramural Programs periodically holds webinars for prospective applicants about NLM's Career Development Awards and Research Project Grant Programs. These sessions (web-based or in-person) are designed for postdoctoral trainees and recent graduates from NLM's university-based training programs, and for other NIs and ESIs. In the webinars NLM staff present an overview of these programs and answer questions from prospective applicants.

A handout of the content is available in PDF Download a PDF copy of the presentation here.

For questions, contact:

Clinical and Public Health Informatics: Dr. Hua-Chuan Sim,
Bioinformatics and Translational Informatics: Dr. Jane Ye,
Consumer Health Informatics and Information Science: Dr. Alan VanBiervliet,

Last Reviewed: June 4, 2018