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PHS 2023-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) (PA-23-230) 


PHS 2023-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) (PA-23-232)  


The National Library of Medicine (NLM) offers support for research and development projects in biomedical informatics and data science. NLM defines biomedical informatics as the science of optimal organization, management, presentation and utilization of information relevant to medicine and biology. The informatics projects of interest to NLM involve the application of computer and information sciences to information problems in a biomedical domain. For additional information about areas of interest to NLM and a listing of NLM funded applications, please visit // Business concerns interested in exploring SBIR/STTR grant opportunities with NLM are encouraged to contact the NLM representatives prior to submitting an application. 
NLM’s SBIR/STTR grant programs are focused on areas of particular interest from small business. The following narrative indicates the scope of projects suitable for the SBIR/STTR program that fit within the mission of NLM. They are not listed in priority order.

  • Visualization approaches or techniques for complex biomedical data at multiple levels
  • Artificial Intelligence techniques for characterizing and minimizing the impact of errors, incompleteness, missingness, within health-related data sets
  • Novel platforms, technologies, tools, and techniques for: (1) integration of patient data collected from multiple devices and clinical studies and (2) integration of large heterogeneous biomedical data resources
  • Technological approaches to protect biomedical data confidentiality during storage and sharing
  • Development of new, innovative tools and methods for annotating, curating, and managing biomedical data resources
  • Tools to enhance security of biomedical data, including personal health data
  • Novel methods to facilitate real-time decision-making in clinical practice and public health, using personal health data in electronic records or clinical trials
  • Tools, technologies and other strategies to track disease outbreaks, epidemics, pandemics
  • Tools and technologies for understanding and predicting climate and environmental effects on human health

NLM Contact

Allison Dennis, PhD
Program Officer



January 5, April 5, September 5 each year
Full listing of deadlines for competing applications: //

This FOA expires on April 6, 2024. 

Last Reviewed: November 2, 2023