New and Updated Sources (Expanded Representation Information) - 2022AB Release
General Information:What's New to the Metathesaurus
For 2022AB, there is one new source (ORPHANET), three new translations (LNC-UK-UA, MDRLAV, MDRSWE), and 65 updated sources (including translation sources and subsources).
ORPHANET is a resource for gathering and improving knowledge on rare
diseases. Its aim is to improve the diagnosis, care and treatment of patients with rare diseases.
LNC-UK-UA is the Ukrainian, Ukraine Edition of LOINC (LNC).
MDRLAV is the Latvian Edition of the Medical Dictionary of Regulatory Activities Terminology (MedDRA).
MDRSWE is the Swedish Edition of the Medical Dictionary of Regulatory Activities Terminology (MedDRA).
For detailed information about sources that are new or have had changes made (e.g., new term types, new attribute names, etc.):
Current Procedural Terminology, CPT2022
HUGO Gene Nomenclature Committee, HGNC2022_04
LOINC, LNC273
LOINC, German, Germany Edition, LNC-DE-DE_273
LOINC, Ukrainian, Ukraine Edition, LNC-UK-UA_273
Medical Dictionary for Regulatory Activities Terminology (MedDRA), Latvian Edition, MDRLAV25_0
Medical Dictionary for Regulatory Activities Terminology (MedDRA), Swedish Edition, MDRSWE25_0
German translation of the Medical Subject Headings, MSHGER2022
NCI Thesaurus, NCI2021_04D
Orphanet Nomenclature, ORPHANET_2022_06
SNOMED Clinical Terms, Spanish Language Edition, SCTSPA_2022_04_30
US Edition of SNOMED CT, SNOMEDCT_US_2022_09_01
Veterinary Extension to SNOMED CT, SNOMEDCT_VET_2022_04_01
------------------------------------------
What's New to the Metathesaurus:
Attribute Name (ATN):
GENCC
MANE_SELECT
CLINVAR_VARIATION_ID
Relationship Attribute (RELA) | Inverse:
before|after
has_dipg_dmg_permissible_value|is_dipg_dmg_permissible_value_for_variable
has_pcdc_hl_permissible_value|is_pcdc_hl_permissible_value_for_variable
has_pcdc_os_permissible_value|is_pcdc_os_permissible_value_for_variable
partially_equivalent_to|partially_equivalent_to
possibly_replaced_by|possibly_replaces
process_acts_on|acted_on_by_process
-------------------------------------------------------
Source: Current Procedural Terminology
VSAB: CPT2022
RVU attributes were not available for CPT2022. They will be included in CPT2023.
-------------------------------------------------------
Source: HUGO Gene Nomenclature Committee
VSAB: HGNC2022_04
New attribute name(s) (ATN) | Description:
GENCC|HGNC ID used within the GenCC database
MANE_SELECT|NCBI and Ensembl transcript IDs/accessions for one high-quality representative transcript per protein-coding gene.
Discussion:
1. New ATN = GENCC contains the "HGNC ID used within the GenCC
database as the unique identifier of their gene reports within the
GenCC database."
2. New ATN = MANE_SELECT contains "NCBI and Ensembl transcript
IDs/accessions including the version number for one high-quality
representative transcript per protein-coding gene that is well-
supported by experimental data and represents the biology of the gene".
-------------------------------------------------------
Source: LOINC
VSAB: LNC273
1. New abbreviation | Class:
ENDO.PULM|Endo Pulmonary
2. Dropped attribute name(s) (ATN) | Description:
EXAMPLE_SI_UCUM_UNITS|EXAMPLE_SI_UCUM_UNITS
UNITS_AND_RANGE|Units and range
3. Refreshed rankings of commonly used LOINC codes in the U.S.
Discussion:
Refreshed rankings of the 20,000 most commonly used LOINC codes in the U.S. These
rankings replace the previous "Top 2000" lab codes which were out of date and
included only lab. The new rankings encompass clinical as well and are in the
COMMON_TEST_RANK field of the Loinc.csv file.
-------------------------------------------------------
Source: LOINC, German, Germany Edition
VSAB: LNC-DE-DE_273
New termtype(s) (TTY) | Description:
LO|Obsolete official fully specified name
OLC|Obsolete Long common name
Discussion:
Termtypes LO and OLC have been populated once again after having been
deprecated in previous versions.
-------------------------------------------------------
Source: LOINC, Ukrainian, Ukraine Edition
VSAB: LNC-UK-UA_273
New termtype(s) (TTY) | Description:
LC|Long common name
LN|LOINC official fully specified name
LVDN|Linguistic variant display name
OSN|Official short name
Discussion:
New translation source.
-------------------------------------------------------
Source: Medical Dictionary for Regulatory Activities Terminology (MedDRA),
Latvian Edition
VSAB: MDRLAV25_0
1. New termtype(s) (TTY) | Description:
AB|Abbreviation in any source vocabulary
HG|High Level Group Term
HT|Hierarchical term
LLT|Lower Level Term
OL|Non-current Lower Level Term
OS|System-organ class
PT|Designated preferred name
SMQ|Standardised MedDRA Query
2. New relationship | relationship attribute (RELA) | RELA inverse:
RO|classifies|classified_as
RO|has_member|member_of
RO|member_of|has_member
SY|expanded_form_of|has_expanded_form
SY|translation_of|has_translation
3. New attribute name (ATN) | Description:
MISO|MedDRA Serial Code International SOC Sort Order Digit (01-26)
MPS|MedDRA primary SOC
SMQ_ALGO|Standardised MedDRA Query (SMQ) Algorithm. Boolean expression
of algorithm for the SMQ.
SMQ_LEVEL|Standardised MedDRA Query (SMQ) Level. Value between 1 and 5
identifying the level of the SMQ within the hierarchy of SMQs.
SMQ_SOURCE|Standardised MedDRA Query (SMQ) Source. Source for the
development of the SMQ.
SMQ_STATUS|Standardised MedDRA Query (SMQ) Status. "A" = active; "I" =
inactive.
SMQ_TERM_ADDVERSION|Standardised MedDRA Query (SMQ) Addition Version.
Version of MedDRA in which term was added to the SMQ.
SMQ_TERM_CAT|Standardised MedDRA Query (SMQ) Term Category. A single
alphabetical letter indicating the category of the term for application
of the SMQ algorithm.
SMQ_TERM_LEVEL|Standardised MedDRA Query (SMQ) Term Level. The MedDRA
hierarchy level of a term.
SMQ_TERM_LMVERSION|Standardised MedDRA Query (SMQ) Last Modified
Version. Version of MedDRA in which term was last modified in the SMQ.
SMQ_TERM_SCOPE|Standardised MedDRA Query (SMQ) Term Scope. Defines the
MedDRA term as a member of the broad scope (1), narrow scope (2) of the
SMQ search, or a child SMQ (0) (zero).
SMQ_TERM_STATUS|Standardised MedDRA Query (SMQ) Term Status. Identifies
a term as active ("A") or inactive ("I") within this SMQ.
SMQ_TERM_WEIGHT|Standardised MedDRA Query (SMQ) Term Weight. Used for
some SMQ algorithms; "0" is used as default.
SOS|Scope Statement
Discussion:
New translation source.
----------------------------------------
Source: Medical Dictionary for Regulatory Activities Terminology (MedDRA),
Swedish Edition
VSAB: MDRSWE25_0
1. New termtype(s) (TTY) | Description:
AB|Abbreviation in any source vocabulary
HG|High Level Group Term
HT|Hierarchical term
LLT|Lower Level Term
OL|Non-current Lower Level Term
OS|System-organ class
PT|Designated preferred name
SMQ|Standardised MedDRA Query
2. New relationship | relationship attribute (RELA) | RELA inverse:
RO|classifies|classified_as
RO|has_member|member_of
RO|member_of|has_member
SY|expanded_form_of|has_expanded_form
SY|translation_of|has_translation
3. New attribute name (ATN) | Description:
MISO|MedDRA Serial Code International SOC Sort Order Digit (01-26)
MPS|MedDRA primary SOC
SMQ_ALGO|Standardised MedDRA Query (SMQ) Algorithm. Boolean expression
of algorithm for the SMQ.
SMQ_LEVEL|Standardised MedDRA Query (SMQ) Level. Value between 1 and 5
identifying the level of the SMQ within the hierarchy of SMQs.
SMQ_SOURCE|Standardised MedDRA Query (SMQ) Source. Source for the
development of the SMQ.
SMQ_STATUS|Standardised MedDRA Query (SMQ) Status. "A" = active; "I" =
inactive.
SMQ_TERM_ADDVERSION|Standardised MedDRA Query (SMQ) Addition Version.
Version of MedDRA in which term was added to the SMQ.
SMQ_TERM_CAT|Standardised MedDRA Query (SMQ) Term Category. A single
alphabetical letter indicating the category of the term for application
of the SMQ algorithm.
SMQ_TERM_LEVEL|Standardised MedDRA Query (SMQ) Term Level. The MedDRA
hierarchy level of a term.
SMQ_TERM_LMVERSION|Standardised MedDRA Query (SMQ) Last Modified
Version. Version of MedDRA in which term was last modified in the SMQ.
SMQ_TERM_SCOPE|Standardised MedDRA Query (SMQ) Term Scope. Defines the
MedDRA term as a member of the broad scope (1), narrow scope (2) of the
SMQ search, or a child SMQ (0) (zero).
SMQ_TERM_STATUS|Standardised MedDRA Query (SMQ) Term Status. Identifies
a term as active ("A") or inactive ("I") within this SMQ.
SMQ_TERM_WEIGHT|Standardised MedDRA Query (SMQ) Term Weight. Used for
some SMQ algorithms; "0" is used as default.
SOS|Scope Statement
Discussion:
New translation source.
----------------------------------------
Source: German translation of the Medical Subject Headings
VSAB: MSHGER2022
Dropped attribute name (ATN) | Description:
TERMUI|Term unique identifier
----------------------------------------
Source: NCI Thesaurus
VSAB: NCI2022_04D
1. Subsources are no longer included in the UMLS. To access NCI subsources, refer to the NCI Metathesaurus (https://ncim.nci.nih.gov/ncimbrowser/).
2. New relationship | relationship attribute (RELA) | RELA inverse:
RO|has_dipg_dmg_permissible_value|is_dipg_dmg_permissible_value_for_variable
RO|has_pcdc_hl_permissible_value|is_pcdc_hl_permissible_value_for_variable
RO|has_pcdc_os_permissible_value|is_pcdc_os_permissible_value_for_variable
3. New attribute name (ATN) | Description:
CLINVAR_VARIATION_ID|CLINVAR VARIATION ID
Discussion:
All subsource content has been removed from NCI Thesaurus in the UMLS, however,
a list of the subsources can be found on the NCI Thesaurus source
vocabulary documentation page (https://www.nlm.nih.gov/research/umls/sourcereleasedocs/current/NCI/index.html).
Users interested in the codes and names from the NCI Thesaurus
subsources can still find them in the NCI Thesaurus
(https://ncit.nci.nih.gov/ncitbrowser/) or the NCI Metathesuarus
(https://ncim.nci.nih.gov/ncimbrowser/).
-----------------------------------------------
Source: Orphanet Nomenclature
VSAB: ORPHANET_2022_06
New termtype(s) (TTY) | Description:
PT|Designated preferred name
SY|Designated synonym
Discussion:
New source.
----------------------------------------
Source: RXNORM Vocabulary
VSAB: RXNORM_20AA_220906F
This version includes:
ATC_2022_22_09_06 (Anatomical Therapeutic Chemical Classification System)
CVX_2022_06_23_22_09_06 (Vaccines Administered)
DRUGBANK5.0_2022_08_01 (DrugBank)
GS_2022_08_05 (Gold Standard Drug Database)
MMSL_2022_08_01 (Multum MediSource Lexicon)
MMX_2022_08_08 (Micromedex RED BOOK)
MTHCMSFRF_2020_22_09_06 (Metathesaurus CMS Formulary Reference File)
MTHSPL_2022_08_26 (Metathesaurus FDA Structured Product Labels)
NDDF_2022_08_10 (FDB MedKnowledge)
USP_2022_08_12 (USP Compendial Nomenclature)
VANDF_2022_07_29 (Veterans Health Administration National Drug File)
-----------------------------------------------
Source: SNOMED Clinical Terms, Spanish Language Edition
VSAB: SCTSPA_2022_04_30
New attribute name (ATN) | Description:
REFSET_PATTERN|Refset pattern
----------------------------------------
Source: US Edition of SNOMED CT
VSAB: SNOMEDCT_US_2022_09_01
New relationship | relationship attribute (RELA) | RELA inverse:
RO|before|after
RO|partially_equivalent_to|partially_equivalent_to
RO|possibly_replaced_by|possibly_replaces
RO|process_acts_on|acted_on_by_process
---------------------------------------------------------------------
Source: Veterinary Extension to SNOMED CT
VSAB: SNOMEDCT_VET_2022_04_01
New attribute name (ATN) | Description:
LANGUAGECODE|SNOMED CT string identifying a language and, if appropriate,
a dialect in which this description is valid.
Last Reviewed: November 6, 2022