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Unified Medical Language System® (UMLS®)

RxNorm Release Notes - April 7, 2025

For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.

Sources

The following sources have been updated since the previous RxNorm release:

Source Name Source Abbreviation (SAB) Version
Vaccines Administered CVX CVX_2025_03_21
DrugBank DRUGBANK DRUGBANK5.0_2025_03_06
Gold Standard Drug Database GS GS_2025_03_07
Multum MediSource Lexicon MMSL MMSL_2025_03_01
Micromedex RED BOOK MMX MMX_2025_02_28
FDA Structured Product Labels MTHSPL MTHSPL_2025_03_29
FDB MedKnowledge (formerly NDDF Plus) NDDF NDDF_2025_03_05
RxNorm normalized names and codes RXNORM RXNORM_20AA_250407F
Veterans Health Administration National Drug File VANDF VANDF_2025_02_28

The following sources have not been updated since the previous RxNorm release:

Source Name Source Abbreviation (SAB) Version
Anatomical Therapeutic Chemical Classification System ATC ATC_2025_02_10
CMS Formulary Reference File MTHCMSFRF MTHCMSFRF_2020
US Edition of SNOMED CT (drug information) SNOMEDCT_US SNOMEDCT_US_2025_01_31
USP Compendial Nomenclature USP USP_2025_01_30

*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact: medispan-support@wolterskluwer.com.

RxNorm Data Changes

No major changes.

RxMix

Did you know that you can share RxMix workflows by simply copying the URL and sharing it? For example, here is a workflow that will find drug class information for an NDC (click “Run”):

https://mor.nlm.nih.gov/RxMix/#?q=rxnorm.findRxcuiById%0A%20(allsrc%3A%220%22%2C%20%0A%20%20idtype%3A%22NDC%22)%3AidGroup.rxnormId%0Arxclass.getClassByRxNormDrugId%0A%20(relaSource%3A%22ALL%22%2C%20%0A%20%20relas%3A%22ALL%22)%3ArxclassDrugInfoList.rxclassDrugInfo&s=v&v=00169413211

RxMix is a web interface that can do batch processing of RXCUIs, NDCs, and drug names to produce useful reports by integrating the RxNorm, RxClass, and RxTerms APIs. For more information, see the RxMix Tutorial: https://lhncbc.nlm.nih.gov/RxNav/applications/RxMixTutorial.html

Data Counts

Term Type or Attribute Number
Active GPCKs 623
Active BPCKs 732
Active SCDs 17517
Active SBDs 9636
Active RXNORM MINs 3814
Active RXNORM INs 14525
Active RXNORM PINs 3558
Active RXNORM BNs 5081
Active RXNORM DFs 122
   
Obsolete GPCKs 260
Obsolete BPCKs 241
Obsolete SCDs 19672
Obsolete SBDs 11998
Obsolete RXNORM MINs 0
Obsolete RXNORM INs 0
Obsolete RXNORM PINs 0
Obsolete RXNORM BNs 6559
Obsolete RXNORM DFs 65
Editor-suppressed SCDs 2115
Editor-suppressed SBDs 1748
SAB=RXNORM NDCs 248144
Distinct SAB=RXNORM NDCs 248144

Last Reviewed: April 7, 2025