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RxNorm Release Notes - October 6, 2025

For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.

Sources

The following sources have been updated since the previous RxNorm release:

Source NameSABVersion
Vaccines AdministeredCVXCVX_2025_09_23
DrugBankDRUGBANKDRUGBANK5.0_2025_09_04
Gold Standard Drug DatabaseGSGS_2025_09_05
Multum MediSource LexiconMMSLMMSL_2025_09_01
Micromedex RED BOOKMMXMMX_2025_08_29
Metathesaurus FDA Structured Product LabelsMTHSPLMTHSPL_2025_09_26
FDB MedKnowledge (formerly NDDF Plus)NDDFNDDF_2025_09_03
RxNorm VocabularyRXNORMRXNORM_20AA_251006F
Veterans Health Administration National Drug FileVANDFVANDF_2025_08_29

The following sources have not been updated since the previous RxNorm release:

Source NameSABVersion
Anatomical Therapeutic Chemical Classification SystemATCATC_2025_02_10
Metathesaurus CMS Formulary Reference FileMTHCMSFRFMTHCMSFRF_2020
US Edition of SNOMED CTSNOMEDCT_USSNOMEDCT_US_2025_07_31
USP Compendial NomenclatureUSPUSP_2025_01_30

*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact: medispan-support@wolterskluwer.com.

Data Counts

Term Type or AttributeNumber
Active RXNORM GPCKs640
Active RXNORM BPCKs743
Active RXNORM SCDs17527
Active RXNORM SBDs9713
Active RXNORM MINs3823
Active RXNORM INs14584
Active RXNORM PINs3599
Active RXNORM BNs5139
Active RXNORM DFs126
Obsolete RXNORM GPCKs258
Obsolete RXNORM BPCKs244
Obsolete RXNORM SCDs19938
Obsolete RXNORM SBDs12162
Obsolete RXNORM MINs0
Obsolete RXNORM INs0
Obsolete RXNORM PINs0
Obsolete RXNORM BNs6612
Obsolete RXNORM DFs65
Editor-suppressed RXNORM SCDs2149
Editor-suppressed RXNORM SBDs1777
SAB=RXNORM NDCs251525
Distinct SAB=RXNORM NDCs251525

Last Reviewed: September 30, 2025