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Unified Medical Language System® (UMLS®)

DRUGBANK Source Information

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Source Synopsis

Web site:
http://www.drugbank.ca/

Authority
The DrugBank database is supported by the Canadian Institutes of Research, Alberta Innovates - Health Solutions, and The Metabolomics Innovation Centre (TMIC).

Purpose
DrugBank combines information on drugs and drug targets.

Description
Drug entries include FDA-approved small molecule and biotech drugs, nutraceuticals and experimental drugs as well as non-redundant protein sequences linked to the drugs.

Update Frequency
DrugBank is updated daily.

RxNorm Update Frequency
DrugBank is updated in each RxNorm monthly release.

Sites Consulted

DrugBank [Internet]. [place unknown: publisher unknown]; [cited 2017 June 20]. Available from http://www.drugbank.ca/; Frequently Asked Questions (FAQ): https://www.drugbank.ca/faqs

Source Representation

This section lists specific source data elements and provides information on their representation in RxNorm.

Summary of Changes

There are no changes to the original data format or to RxNorm source processing.

Source Provided Files:

The file is available at https://portal.drugbankplus.com/

The following file is used for RxNorm source processing.

File Name Description
Drugs.json Json File

Source-Provided Files: Details

The following is a list of fields in the DrugBank source file used in RxNorm:

Field Name Description
Primary _accession_number Unique DrugBank accession number consisting of a 2-letter prefix (DB) and a 5-number suffix. This ID is used to access the drug entry via the URL. If an entry is deleted, it's DrugBank ID will not be reused.
Secondary_accession_number It consists of the 4-letter prefix and a 5-number suffix. Each accession number is unique to the drug's generic name. The 4-letter suffix (APRD, EXPT, BIOD, NUTR) indicates the type of drug (APRD=approved small molecule drug, EXPT=experimental drug, BIOD=biotech drug, NUTR=nutraceutical or natural product).
Name Standard name of drug as provided by drug manufacturer.
Synonym Alternate names of the drug
UNII FDA UNII code
Language Language of Synonym

DrugBank Field Representation in RxNorm Files:

Field Representation
Primary _accession_number RXNCONSO.CODE
Secondary_accession_number RXNSAT.ATN = SID
Name RXNCONSO.STR
CODE = Primary_accession_number
TTY = "IN"
SUPPRESS = "N"
Synonym RXNCONSO.STR
CODE = Primary_accession_number
TTY = "SY" or "FSY" (TTY = SY when Language field is "english"; TTY = FSY when Language field is not "english")
SUPPRESS = "N"
UNII RXNSAT.ATN = FDA_UNII_CODE
Language Not represented in RxNorm but used to process TTY = "SY" or "FSY"

RxNorm Representation

This section lists RxNorm data elements and traces them back to the specific DrugBank data that populates them.

Summary of Changes

There are no changes to the original data format or to RxNorm source processing.

Source Provided Files:

The file is available at https://portal.drugbankplus.com/

The following file is used for RxNorm source processing.

File Name Description
Drugs.json Json File

RxNorm Identifiers:

Identifiers are assigned as follows:

Identifier Origin
CODE Primary_accession_number
SAUI Not Applicable
SCUI Not Applicable
SCUI Not Applicable

Atoms (RXNCONSO):

Term Type Origin
IN Name
SY Synonym
(Language = "english")
FSY Synonym
(Language = foreign language such as Latin)

Relationships (RXNREL):

No relationships are provided for this source.


Attributes (RXNSAT):

ATN Origin
SID Secondary_accession_number
FDA_UNII_CODE UNII