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Unified Medical Language System® (UMLS®)

USP Source Information

Click on a topic below the Source Synopsis section to display details.

Source Synopsis

Web site:
http://www.usp.org/health-quality-safety/compendial-nomenclature

Authority
The United States Pharmacopeia (USP) Compendial Nomenclature is a product supported by the United States Pharmacopeial Convention.

Purpose
The USP Compendial Nomenclature provides official substance and official preparation (product) naming for Food and Drug Administration (FDA)-approved drugs and their ingredients.

Description
The USP Compendial Nomenclature contains names and identifiers of an official substance or official preparation (product). The presence of an identifier code signifies potential or current work on the nomenclature of a drug.

Update Frequency
The USP Compendial Nomenclature is updated monthly.

RxNorm Update Frequency
Updated in each RxNorm monthly release.

Sites Consulted

Compendial Nomenclature [Internet]. [place unknown: publisher unknown]; [cited 2018 August 14]. Available from http://www.usp.org/health-quality-safety/compendial-nomenclature

Use of Drug Name Terms Policy [Internet]. [place unknown: publisher unknown]; [cited 2018 August 14]. Available from https://www.fda.gov/Drugs/DevelopmentApprovalProcess/FormsSubmissionRequirements/ElectronicSubmissions/DataStandardsManualmonographs/ucm071638.htm

Metadata

Field Value
Short NameUSP Compendial Nomenclature
FamilyUSP
Source Restriction Level0
LanguageENG
License ContactSteven Emrick
Senior HIT Product Manager
United States Pharmacopeia
12601 Twinbrook Parkway
Rockville
MD
US
20852-1790
1-800-227-8772
HealthcareQuality@usp.org
http://www.usp.org/health-quality-safety
Content ContactSteven Emrick
Senior HIT Product Manager
United States Pharmacopeia
12601 Twinbrook Parkway
Rockville
MD
US
20852-1790
1-800-227-8772
HealthcareQuality@usp.org
http://www.usp.org/health-quality-safety

Source Representation

This section lists specific source data elements and provides information on their representation in RxNorm.

Summary of Changes

There are no changes to the original data format or to RxNorm source processing.

Source Provided Files:

The files will be made available on the USP website later in the year.

The following file is used for RxNorm source processing.

File Name Description
usp-compendial-nomenclature-yyyy-mm.xlsx.xlsx Excel File

Source-Provided Files: Details

The following is a list of fields in the USP source file used in RxNorm:

File name: usp-compendial-nomenclature-yyyy-mm.xlsx
Field Name Description
monograph_identifier A meaningless alphanumeric string starting with the letter ‘m’ that provides encoding for the monograph.
monograph_name The title of the monograph.
monograph_type The monograph type represents a quality standard for either a drug “substance” (e.g. “Warfarin Sodium”) or drug “product” (e.g. “Warfarin Sodium Tablets”).
monograph_status Values for this field are one of the following:
  • Official Monograph: The monograph is legally enforceable as of the date in the ‘monograph_official_date’ field
  • Pending Official Monograph: The monograph has been finalized and will become official as of the date in the ‘monograph_official_date’ field
  • Nomenclature Finalized: The name of the monograph has been balloted, but a monograph is not yet available
monograph_official_date The date when the monograph became official or will become official, depending on the value of the ‘monograph_status’ field.

USP Field Representation in RxNorm Files:

Field RxNorm Representation
monograph_identifier RXNCONSO.CODE
monograph_name RXNCONSO.STR
monograph_type Term Type (TTY)
TTY = IN when value is Substance
TTY = CD when value is Product
monograph_status RXNSAT.ATN = MONOGRAPH_STATUS
monograph_official_date RXNSAT.ATN = MONOGRAPH_OFFICIAL_DATE

RxNorm Representation

This section lists RxNorm data elements and traces them back to the specific USP data that populates them.

Summary of Changes

There are no changes to the original data format or to RxNorm source processing.

Source Provided Files:

The file will be made available on the USP website later in the year.

The following file is used for RxNorm source processing.

File Name Description
usp-compendial-nomenclature-yyyy-mm.xlsx Excel File

RxNorm Identifiers:

Identifiers are assigned as follows:

Identifier Origin
CODE monograph_identifier
SAUI Not applicable
SCUI Not applicable
SDUI Not applicable

Atoms (RXNCONSO):

Term Type Origin
IN monograph_name when monograph_type = Substance
CD monograph_name when monograph_type = Product

Relationships (RXNREL):

Clinical Drug (TTY = CD):

Atom Type 1 Atom Type 2 Relationship
Clinical Drug (CD) Semantic Clinical Drug Form (SCDF) product_monograph_title_of

Semantic Clinical Drug Form (TTY = SCDF):

Atom Type 1 Atom Type 2 Relationship
Semantic Clinical Drug Form (SCDF) Clinical Drug (CD) has_product_monograph_title

Attributes (RXNSAT):

ATN Origin
MONOGRAPH_STATUS monograph_status
MONOGRAPH_OFFICIAL_DATE monograph_official_date

Data Examples with Sample Database Queries

This section lists source terminology specific data examples and sample database queries using Structured Query Language (SQL) to obtain the data. For more information about RxNorm data and files, see the RxNorm Technical Documentation.

Names and Codes in RXNCONSO.RRF

Here are sample source terminology code, source string, RxNorm Concept Unique Identifier (RXCUI), RxNorm string, term type (TTY), and suppress values.

SOURCE_CODE SOURCE_STR RXCUI RXNORM_STR RXNORM_TTY SUPPRESS
m39860 Ibuprofen 5640 Ibuprofen IN N

Here is a sample database query to retrieve the data above:

SELECT distinct rc1.code as source_code, rc1.str as source_str, rc1.rxcui, rc2.str as rxnorm_str, rc2.tty as rxnorm_tty , rc2.suppress
FROM rxnconso rc1, rxnconso rc2
WHERE rc1.code = 'm39860'
     AND rc1.sab = 'USP'
     AND rc1.rxcui = rc2.rxcui
     AND rc2.sab = 'RXNORM';
    

Names and Relationships in RXNCONSO.RRF and RXNREL.RRF

Here are sample source terminology code, source string, RXCUI, relationship name, RxNorm term type (TTY), RxNorm brand name, and suppress values.

SOURCE_CODE SOURCE_STR RXCUI RELA RXNORM_TTY RXNORM_BN SUPPRESS
m39860 Ibuprofen 5640 has_tradename BN Motrin PM N
m39860 Ibuprofen 5640 has_tradename BN Samson 8 N
m39860 Ibuprofen 5640 has_tradename BN Vicoprofen N
m39860 Ibuprofen 5640 has_tradename BN Neoprofen N

Here is a sample database query to retrieve the data above:

SELECT distinct rc1.code as source_code, rc1.str as source_str, rc1.rxcui, rr.rela, rc2.tty as rxnorm_tty, rc2.str as rxnorm_bn, rc2.suppress
FROM rxnconso rc1, rxnrel rr, rxnconso rc2
WHERE rc1.code = 'm39860'
     AND rc1.sab = 'USP'
     AND rc1.rxcui = rr.rxcui2
     AND rr.rela = 'has_tradename'
     AND rr.rxcui1 = rc2.rxcui
     AND rc2.sab = 'RXNORM'
     AND rc2.tty = 'BN'
     ORDER BY suppress;

Last Reviewed: November 18, 2020