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Brown ArrowEvidence-Based Practice and Health Technology Assessment

Evidence-Based Practice: "A way of providing health care that is guided by a thoughtful integration of the best available scientific knowledge with clinical expertise. This approach allows the practitioner to critically assess research data, clinical guidelines, and other information resources in order to correctly identify the clinical problem, apply the most high-quality intervention, and re-evaluate the outcome for future improvement." 2009 Medical Subject Headings (MeSH).

Health technology assessment (HTA): "The systematic evaluation of properties, effects, and/or impacts of health care technology. It may address the direct, intended consequences of technologies as well as their indirect, unintended consequences. Its main purpose is to inform technology-related policymaking in health care. HTA is conducted by interdisciplinary groups using explicit analytical frameworks drawing from a variety of methods." Goodman, Clifford S. HTA 101: Introduction to Health Technology Assessment, January 2004.

Additional information related to Evidence-Based Practice/Health Technology Assessment may be found in the Comparative Effectiveness Research (CER) Main Topic.

Search Tools from NLM

  • HSRR (Health Services and Sciences Research Resources) - (National Library of Medicine, National Information Center on Health Services Research and Health Care Technology)  Details

    HSRR is a searchable database of information about research datasets, instruments/indices and software employed in Health Services Research, the Behavioral and Social Sciences and Public Health. The database includes brief descriptions of research resources and links to PubMed.

  • PubMed Clinical Queries - (National Library of Medicine (NLM) U.S.)  Details

    A searching tool based on the work of Haynes, et al, to filter results via a series of evidence filters.

News: Evidence-based Practice/HTA

Databases of Guidelines

  • Cochrane Collaboration Evidence Reviews - (Cochrane Collaboration)  Details

    Cochrane Reviews are published in The Cochrane Library - an online collection of databases that brings together in one place rigorous and up-to-date research on the effectiveness of healthcare treatments and interventions, as well as methodology and diagnostic tests.

  • EPC Evidence Reports - (Agency for Healthcare Research and Quality (AHRQ))  Details

    AHRQ is developing scientific information for other agencies and organizations on which to base clinical guidelines, performance measures, and other quality improvement tools. Contractor institutions review all relevant scientific literature on assigned clinical care topics and produce evidence reports and technology assessments, conduct research on methodologies and the effectiveness of their implementation, and participate in technical assistance activities.

  • Knowledge Translation (KT+) - (Canadian Obesity Network Canada, McMaster University Health Information Research Unit Canada)  Details

    KT+ provides access to articles on the current evidence on knowledge translation including articles on quality improvement, continuing medical education, computerized clinical decision support, health services research and patient adherence. Its purpose is to inform those working in the knowledge translation area of current research as it is published.

  • Strings Attached: CADTH's Database Search Filters - (Canadian Agency for Drugs and Technologies in Health (CADTH) Canada)  Details

    Included are search filters for Pubmed, OVID Medline, Embase, PSYCInfo filters on: Systematic Reviews/Meta-Analysis/Health Technology Assessment, Randomized Controlled Trials, Guidelines, Economic Evaluations/Cost/Economic Models, Health Utilities/Quality of Life, Narrow Economic filter.

Meetings, Conferences, Webinars

  • BIO International Convention - (Biotechnology Industry Organization (BIO))  Details

    Held in June of each year, the annual meeting represents research and development of innovative healthcare, agricultural, industrial and environmental biotechnology products. Locations vary.

  • G-I-N Conference 2016 - (Guidelines International Network (GIN))  Details

    September 27-30, 2016. Philadelphia, PA. Conference theme is "Individualised guidelines and clinical performance measurement in an era of personalised medicine."

  • Medicine: Mind the Gap Series - (National Institutes of Health (NIH))  Details

    This seminar series examine issues that surround the areas of research, evidence, and clinical practice. The seminars are available in person at the NIH in Bethesda, MD or via free webcast.

Past Webinars & Meetings

  • Eisenberg Center Conference Series - (Agency for Healthcare Research and Quality (AHRQ))  Details

    Streaming video and conference proceedings from past seminars are available. The conference discusses of state-of-the-art concepts in communication and medical decisionmaking.

  • The Limits of Evidence-based Medicine - (University of Washington)  Details

    A video of Laboratory Medicine Grand Rounds, Dr. Mark Tonelli held on February 10, 2016, in which EBM, its strengths and weaknesses, and the relationship with clinical practice is discussed. The value of case-based medicine to the clinical process is also discussed.

Key Organizations

  • AHRQ Effective Healthcare - (Agency for Healthcare Research and Quality (AHRQ))  Details

    The Effective Health Care Program is dedicated to facilitating decision making by providing findings from high-quality research in formats for different audiences.

  • Accelerating Change and Transformation in Organizations and Networks II (ACTION II) - (Agency for Healthcare Research and Quality (AHRQ))  Details

    ACTION II is a model of field-based research designed to promote innovation in health care delivery by accelerating the diffusion of research into practice. The ACTION II network includes 17 large partnerships and more than 350 collaborating organizations that provide health care to an estimated 50 percent of the U.S. population. ACTION II promotes and accelerates the development, implementation, dissemination, and sustainability of innovations in health care delivery to increase understanding of how to incorporate evidence-based improvements into routine practice to improve quality of care.

  • Canadian Agency for Drugs and Technologies in Health Details

    National body that provides Canada's federal, provincial and territorial health care decision makers with credible, impartial advice and evidence-based information about the effectiveness and efficiency of drugs and other health technologies. It was formerly known as the Canadian Coordinating Office for Health Technology Assessment (CCOHTA)

  • Center for Evidence-based Policy - (Oregon Health & Science University (OHSU) US)  Details

    The Center is a national leader in evidence-based decision making and policy design, working with federal, state and local policymakers in more than 20 states to use high-quality evidence to guide decisions, maximize resources and improve health outcomes.

  • Centre for Evidence-Based Medicine Details

    Aims to develop, teach and promote evidence-based health care and provide support and resources to doctors and health care professionals to help maintain the highest standards of medicine.

  • Centre for Reviews and Dissemination Details

    Part of the National Institute for Health Research, CRD undertakes high quality systematic reviews that evaluate the effects of health and social care interventions and the delivery and organisation of health care.

  • Cochrane Collaboration Details

    Improving healthcare decision-making globally, through systematic reviews of the effects of healthcare interventions.

  • ECRI Institute Details

    An independent, nonprofit health services research agency that works to improve the quality, safety, and cost-effectiveness of patient care. Provides a wide range of services dealing with healthcare technology, including research, evaluation, assessment, publications, and databases. Other areas of interest include: healthcare risk and quality management, and healthcare environmental management.

  • EUnetHTA (European Network for Health Technology Assessment) Details

    Focusing on scientific cooperation in HTA in Europe, thirty four government appointed organisations from the EU Member States, Accession Countries and EEA work together to help developing reliable, timely, transparent and transferable information to contribute to HTAs in European countries. The EUnetHTA Joint Action builds on the achievements of a number of the previous European initiatives including the EUnetHTA Project (2006-2008) and the Pharmaceutical Forum (on relative effectiveness).

  • Effective Healthcare Program - (Agency for Healthcare Research and Quality (AHRQ))  Details

    Funds individual researchers, research centers, and academic organizations to work together with AHRQ to produce effectiveness and comparative effectiveness research for clinicians, consumers, and policymakers.

  • Equator Network Details

    This initiative seeks to improve the reliability and value of published health research literature by promoting transparent and accurate reporting and wider use of robust reporting guidelines. The website contains a blog, a library for health research reporting, a toolkit to promote accurate publication of health research, and upcoming and past events and classes.

  • Evidence-based Practice Centers (EPC) Program - (Agency for Healthcare Research and Quality (AHRQ))  Details

    Under the Evidence-based Practice Centers (EPC) Program of five-year contracts are awarded to institutions in the United States and Canada to serve as EPCs. The EPCs review all relevant scientific literature on clinical, behavioral, and organization and financing topics to produce evidence reports and technology assessments. These reports are used for informing and developing coverage decisions, quality measures, educational materials and tools, guidelines, and research agendas. The EPCs also conduct research on methodology of systematic reviews.

  • Evidence-based Practice Centers (EPCs) - (Agency for Healthcare Research and Quality (AHRQ))  Details

    Evidence-based Practice Centers (EPCs) are top-ranking institutions where research reviews for the AHRQ Effective Health Care Program are made. EPCs are housed at 15 of the nation's top medical schools, universities, or medical centers. Access research reviews, original research reports, and summary guides.

  • Evidence-based Synthesis Program - (Health Services Research and Development Service, Veterans Administration (HSR&D))  Details

    The Evidence-based Synthesis Program (ESP) was established to provide timely and accurate syntheses of targeted health care topics of particular importance to VA managers and policy makers and to disseminate these reports broadly throughout VA. Access published reports as well as reports in progress.

  • Health Information Research Unit, HIRU, McMaster University Details

    Conducts research in the field of health information science and is dedicated to the generation of new knowledge about the nature of health and clinical information problems, the development of new information resources to support evidence-based health care, and the evaluation of various innovations in overcoming health care information problems.

  • Health Technology Assessment - (Washington State Health Care Authority US)  Details

    The primary purpose of HTA is to ensure medical treatments and services paid for with state health care dollars are safe and proven to work. HTA serves as a resource for state agencies purchasing health care. HTA contracts for scientific, evidence-based reports about whether certain medical devices, procedures, and tests are safe and work as promoted. An independent clinical committee of health care practitioners then uses the reports to determine if programs should pay for the medical device, procedure, or test.

  • Health Technology Assessment International (HTAi) Details

    Focuses uniquely on health technology assessment (HTA) and provides the key forum for all those from the worlds of health care, academia and business interested in the science, development and application of HTA. Health technology assessment (HTA) offers "supporting evidence based decision making in health care policy and practice".

  • Healthcare Delivery Research Program - (National Cancer Institute, NIH (NCI))  Details

    NCI's work related to quality of care research and the translation of this research into practice is available through the links on this website.

  • Insitute of Health Economics - (Institute of Health Economics Canada)  Details

    The IHE strives to assist decision makers in health policy and practice with the results from economic evaluations, costing and cost-effectiveness analyses, and with syntheses of findings from research in health technology assessment.

  • International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Details

    ISPOR promotes the science of pharmacoeconomics (health economics) and outcomes research (the scientific discipline that evaluates the effect of health care interventions on patient well-being including clinical outcomes, economic outcomes, and patient-reported outcomes) and facilitates the translation of this research into useful information for healthcare decision-makers to ensure that society allocates scarce health care resources wisely, fairly and efficiently. ISPOR embraces all health technology assessors, government health technology regulators & payers of health care including governments, insurers, and other health care payers who use health care outcomes research information in their decisions.

  • Joanna Briggs Institute Details

    Based within the University of Adelaide, Australia, the JBI promotes the synthesis, transfer and utilization of evidence by identifying effective healthcare practices to assist in the improvement of healthcare outcomes globally.

  • NExT - Nursing Experts: Translating the Evidence - (University of Illinois at Chicago (UIC))  Details

    The NExT project website is a tool for learning about evidence based public health practice and a portal to evidence based practice resources. The site was developed with a primary audience of public health nurses but will be of interest to everyone interested in learning more about evidence based public health. The site includes a free online course which offers 3 free CEUs to nurses.

  • NHS Health Technology Assessment Programme - (University of Southampton UK)  Details

    The HTA programme is part of the National Institute for Health Research (NIHR). It produces independent research information about the effectiveness, costs and broader impact of healthcare treatments and tests for those who plan, provide or receive care in the NHS.

  • National Institute for Health and Clinical Excellence (NICE) Details

    NICE produces guidance in health technologies with guidance on the use of new and existing medicines, treatments and procedures within the NHS clinical practice; and guidance on the appropriate treatment and care of people with specific diseases and conditions within the NHS.

  • National Quality Forum (NQF) Details

    Not-for-profit membership organization created to develop and implement a national strategy for health care quality measurement and reporting.

  • Quality Enhancement Research Initiative (QUERI) - (Health Services Research and Development Service, Veterans Administration (HSR&D))  Details

    Works to improve the quality of healthcare for veterans by implementing research findings into routine clinical practice. The QUERI centers focus on nine high-risk and/or highly prevalent diseases or conditions among veterans.

  • Swedish Council on Technology Assessment in Health Care (SBU) Details

    SBU presents the scientific evidence on the benefits, risks, and costs associated with different interventions. SBU identifies methods that offer the greatest benefits and the least risk, focusing on the most efficient ways to allocate healthcare resources. However, SBU also identifies methods currently in use that provide no benefits, have not been assessed, or are not cost effective.

  • Technology Assessment Program - (Agency for Healthcare Research and Quality (AHRQ))  Details

    This program provides technology assessments for the Centers for Medicare & Medicaid Services (CMS). AHRQ's technology assessment program uses state-of-the-art methodologies for assessing the clinical utility of medical interventions. Technology assessments are based on a systematic review of the literature, along with appropriate qualitative and quantitative methods of synthesizing data from multiple studies.

Evidence-Based Practice (Domestic)

Evidence-Based Practice items based in the US.

Data, Tools, and Statistics

  • CDC's 6|18 Initiative: Accelerating Evidence into Action - (Centers for Disease Control and Prevention (CDC))  Details

    CDC is partnering with health care purchasers, payers, and providers to improve health and control health care costs. CDC is targeting six common and costly health conditions - tobacco use, high blood pressure, healthcare-associated infections, asthma, unintended pregnancies, and diabetes - and 18 proven specific interventions.

  • Evidence Insight: Video Series - (Mathematica Policy Research, Inc.)  Details

    This video series will examine the research methods that offer the most useful information to policymakers: Bayesian methods, adaptive design RCTs, predictive analytics, and rapid cycle evaluation.

  • Evidence-Based Medicine (EBM) Tutorial - (Duke University Medical Center Library US, University of North Carolina at Chapel Hill Health Science Library US)  Details

    Intended for any health care practitioner or student who needs a basic introduction to the principles of Evidence-Based Medicine.

  • Systematic Review Data Repository - (Agency for Healthcare Research and Quality (AHRQ))  Details

    To assist in the creation of systematic reviews or meta analyses, this tool is designed for the extraction and management of data, and a searchable archive of systematic reviews and their data.

  • Why Not the Best? Comparative Health Care Performance Data - (Commonwealth Fund)  Details

    Free resource for health care professionals interested in tracking performance on various measures of health care quality. It enables organizations to compare their performance against that of peer organizations, against a range of benchmarks, and over time. Case studies and improvement tools spotlight successful improvement strategies of the nation's top performers.

Guidelines, Journals, Other Publications/Tutorials

  • Closing the Quality Gap Series - (Agency for Healthcare Research and Quality (AHRQ))  Details

    This series of reports focuses on improving the quality of health care through critical assessment of relevant evidence for selected settings, interventions, and clinical conditions.

  • EHC Inside Track - (Agency for Healthcare Research and Quality (AHRQ))  Details

    This newsletter covers news related to the Effective Health Care Program.

  • Enabling Medication Management Through Health Information Technology (Health IT) - (Agency for Healthcare Research and Quality (AHRQ))  Details

    This report reviews the literature on the effects of health IT on medication management and synthesizes available evidence regarding the effectiveness and effects of health IT in all phases of medication management as well as reconciliation and education. Gaps are identified; recommendations are made.

  • Ethical Issues in Evidence-Based Medicine - (American Medical Association (AMA))  Details

    This is a special issue of JAMA Virtual Mentor from January 2013, which examines law and ethics regarding EBM. It discusses such areas as education, research, individualized care, and trials.

  • Evidence Based Practice Toolkit for Nursing - (Oregon Health & Science University (OHSU) US)  Details

    This tutorial is designed to support both curriculum-based EBP instruction and the ongoing education of practicing professionals. The tutorial consists of five instructional modules: What is EBP; Asking your question; Levels of evidence; resources; and evidence appraised.

  • A Guide To Evidence-Based Practices (EBP) on The Web - (Substance Abuse & Mental Health Services Administration (SAMHSA))  Details

    SAMHSA provides this Web Guide to assist the public with simple and direct connections to Web sites that contain information about interventions to prevent and/or treat mental and substance use disorders. The Web Guide provides a list of Web sites that contain information about specific evidence-based practices (EBPs) or provide comprehensive reviews of research findings. The Web Guide can be used by stakeholders throughout the behavioral health field to promote awareness of current intervention research and to increase the implementation and availability of EBPs.

  • Implementation Research: A Synthesis of the Literature (2005) images/pdf.gif icon - (Louis de la Parte Florida Mental Health Institute, University of South Florida US)  Details

    This 2005 monograph summarizes findings from the review of the research literature on implementation. The review process began by identifying literature reporting any efforts to collect data on attempts to implement practices or programs in any domain, including agriculture, business, child welfare, engineering, health, juvenile justice, manufacturing, medicine, mental health, nursing and social services.

  • Introduction to Evidence-Based Practice - (Duke University Medical Center Library US)  Details

    This tutorial is intended for any health care practitioner or student who needs a basic introduction to the principles of Evidence-Based Practice.

  • Methods Guide for Comparative Effectiveness Reviews - (Agency for Healthcare Research and Quality (AHRQ))  Details

    Effectiveness and Comparative Effectiveness Reviews, systematic reviews of existing research on the effectiveness, comparative effectiveness, and comparative harms of different health care interventions, are intended to provide relevant evidence to inform real-world health care decisions for patients, providers, and policymakers. In an effort to improve the transparency, consistency, and scientific rigor of the work of the Effective Health Care (EHC) Program, through a collaborative effort, the Agency for Healthcare Research and Quality (AHRQ), the Scientific Resource Center, and the Evidence-based Practice Centers (EPCs) have developed a Methods Guide for Comparative Effectiveness Reviews. We intend that these documents will serve as a resource for our EPCs as well as for other investigators interested in conducting Comparative Effectiveness Reviews.

  • Quality/Equality Glossary - (Robert Wood Johnson Foundation (RWJF))  Details

    A glossary of key terms in the fields of health care quality, disparities reduction and quality improvement.

Evidence-Based Practice (International)

Interational evidence-based practice items.

Data, Tools, and Statistics

  • Health Systems Evidence - (McMaster University Health Information Research Unit Canada)  Details

    Health Systems Evidence is a continuously updated repository of syntheses of research evidence about governance, financial and delivery arrangements within health systems, and about implementation strategies that can support change in health systems.

  • SR Tool Box Details

    The Systematic Review Toolbox is a searchable, web-based catalog of tools that support the systematic review process across multiple domains

Guidelines, Journals, Other Publications

  • Global Health Evidence Evaluation Framework (2013) images/pdf.gif icon - (Agency for Healthcare Research and Quality (AHRQ))  Details

    The Global Health Evidence Evaluation Framework project is aimed at developing an evidence framework for the purposes of informing efficacious, effective, sustainable global health programs at the community and scale level.

Health Technology Assessment

Health Technology Assessment items.

Data, Tools, and Statistics

  • AccessGUDID - (National Library of Medicine (NLM) U.S.)  Details

    Global Unique Device Identification Database (GUDID) contains key device identification information submitted to the FDA about medical devices that have Unique Device Identifiers (UDI).

  • Equity-Oriented Toolkit for Health Technology Assessment (HTA) - (World Health Organization Centre for Knowledge Translation and Health Technology Assessment in Health Equity CA)  Details

    The Equity -Oriented Toolkit is based on a needs-based model of HTA. It provides tools that explicitly consider health equity at the following steps of health technology assessment: Burden of illness, community effectiveness, economic evaluation, and knowledge translation and implementation.

  • Health Technology Assessment Database - (Cochrane Collaboration)  Details

    Brings together details of completed and ongoing health technology assessments (studies of the medical, social, ethical, and economic implications of healthcare interventions) from around the world. The aim of the HTA Database is to improve the quality and cost-effectiveness of health care.

  • Horizon Scan - (Agency for Healthcare Research and Quality (AHRQ))  Details

    Horizon Scan examines emerging health care technologies and innovations to better inform patient-centered outcomes research.

  • ISPOR International Digest of Databases - (International Society for Pharmacoeconomics and Outcomes Research (ISPOR) US)  Details

    Electronic index (Digest) of key attributes of health care databases around the world available at the ISPOR website, which is accessible to the public. The Digest is a compendium of 194 databases. These databases list key attributes of health care data from around the world.

Guidelines, Journals, Other Publications

  • Health Services/Technology Assessment Text (HSTAT) - (National Library of Medicine (NLM) U.S.)  Details

    Health Services/Technology Assessment Text is a searchable collection of large, full-text practice guidelines (including the Guide to Community Preventive Services), technology assessments and health information.

  • Health Technology Assessment of Medical Devices (2011) images/pdf.gif icon - (World Health Organization (WHO))  Details

    WHO has developed a reference document to provide an introduction to the concept and programme of health technology assessment (HTA) around the world and to highlight the contribution that HTA can make to informed policy and decision-making, particularly in developing and emerging countries. It further aims to describe strategic actions that countries can take for introducing HTA into their health systems.

  • HTA Glossary - (Health Technology Assessment International (HTAi) Canada)  Details

    Provides a common vocabulary for work in HTA. Entries in this glossary have been created by selecting terms from existing glossaries (eg. Dr. Clifford Goodman's guide HTA 101) and from terms and sources suggested by many individuals working in the field of HTA.

  • HTAI Policy Forum Papers (free) - (Health Technology Assessment International (HTAi) Canada)  Details

    HTAI has created a subscription journal, which will allow non-members to access policy papers and news/events.