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Background

How is 3D structure determined?

Comparing 3 Primary Techniques

Table comparing experimental techniques for solving 3D biomolecular structure

Where do I find experimentally determined structures?

RCSB Protein Data Bank
NCBI’s Structure Database


NCBI's iCn3D

iCn3D, pronounced "I See in 3D", Structure Viewer is a web-based 3D viewer with structure analysis capabilities. The web-based nature of the tool means no downloads are needed to start visualizing and learning!

iCn3D features of interest:


3D Viewer Feature Comparison:

Table comparing features of various 3D viewers

a: iCn3D aligns structures (PDB or AlphaFold) based on structures or sequences.

b: iCn3D sharable links could be a short URL or a URL containing the address of an iCn3D PNG Image

c: iCn3D supports command-line analysis with either Python scripts or Node.js scripts

d: iCn3D can also be used in Jupyter Notebook

iCn3D Shortcuts and Help Docs:

List of iCn3D shortcuts

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Last Reviewed: April 14, 2023