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For Researchers

Biomedical Literature | Biomedical Topics | Health Services and Public Health | Intramural ResearchHistory of Medicine | Policies and Guidelines

Biomedical Literature

Biomedical Topics

Computational Molecular Biology

    • A tool that finds regions of similarity between biological sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance.
  • GenBank
    • A database of nucleotide sequences.
  • Molecular Structure and Function
    • A database of macromolecular 3D structures, as well as tools for their visualization and comparative analysis.
  • Taxonomy Database
    • A database of taxonomic names of lineages of organisms represented in NCBI's sequence databases.
  • Conserved Domain Database (CDD)
    • A database to identify the conserved domains present in a protein sequence.
  • Reference Sequences (RefSeq)
    • A collection of reference sequences for genomes, gene transcripts, and proteins.
  • Vector Alignment Search Tool (VAST)
    • A computer algorithm developed at NCBI and used to identify similar protein 3-dimensional structures ("similar structures") by purely geometric criteria and to identify distant homologs that cannot be recognized by sequence comparison.

Health Data Standards and Natural Language Processing

Human Genome Resources


Health Services Research and Public Health

Intramural Research

History of Medicine

Policies and Guidelines

Last Reviewed: February 22, 2024