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For Researchers

Biomedical Literature | Biomedical Topics | Health Services and Public Health | Intramural ResearchHistory of Medicine | Policies and Guidelines


Biomedical Literature

Biomedical Topics

Computational Molecular Biology

  • BLAST
    • A tool that finds regions of similarity between biological sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance.
  • GenBank
    • A database of nucleotide sequences.
  • Molecular Structure and Function
    • A database of macromolecular 3D structures, as well as tools for their visualization and comparative analysis.
  • Taxonomy Database
    • A database of taxonomic names of lineages of organisms represented in NCBI's sequence databases.
  • Conserved Domain Database (CDD)
    • A database to identify the conserved domains present in a protein sequence.
  • Reference Sequences (RefSeq)
    • A collection of reference sequences for genomes, gene transcripts, and proteins.
  • Vector Alignment Search Tool (VAST)
    • A computer algorithm developed at NCBI and used to identify similar protein 3-dimensional structures ("similar structures") by purely geometric criteria and to identify distant homologs that cannot be recognized by sequence comparison.

Health Data Standards and Natural Language Processing

Human Genome Resources

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Health Services Research and Public Health

Intramural Research

History of Medicine

Policies and Guidelines

Last Reviewed: February 22, 2024