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Unified Medical Language System® (UMLS®)

RxNorm Release Notes

September Release - 09/06/2016

This release of RxNorm is consistent with the 2016AA UMLS Metathesaurus release. For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm technical documentation.

Sources

The following sources have been updated since the previous RxNorm release:

Source NameSABVersion
Gold Standard Drug Database GS GS_2016_07_29
Medi-Span Master Drug Data Base MDDB MDDB_2016_07_27
Multum MediSource Lexicon MMSL MMSL_2016_08_01
Micromedex RED BOOK MMX MMX_2016_07_25
FDA Structured Product Labels MTHSPL MTHSPL_2016_08_24
FDB MedKnowledge (formerly NDDF Plus) NDDF NDDF_2016_07_27
Veterans Health Administration National Drug File - Reference Terminology NDFRT NDFRT_2016_09_06
NDFRT FDASPL relationships NDFRT_FDASPL NDFRT_FDASPL_2016_09_06
NDFRT FMTSME relationships NDFRT_FMTSME NDFRT_FMTSME_2016_09_06
US Edition of SNOMED CT (drug information) SNOMEDCT_US SNOMEDCT_US_2016_07_31
Veterans Health Administration National Drug File VANDF VANDF_2016_07_22

 

The following sources have not been updated in this release:

Source NameSABVersion
Anatomical Therapeutic Chemical Classification System ATC ATC_2016
Medical Subject Headings (MeSH) MSH MSH2016_2016_02_26
CMS Formulary Reference File MTHCMSFRF MTHCMSFRF_2014

Data Changes

New Dose Form Added
RxNorm includes a new dose form: Transdermal System. This dose form replaces the Transdermal Patch dose form and is defined as an adhesive patch that delivers medication at a set rate systemically over a defined period of time. All drugs previously using the Transdermal Patch dose form now have the Transdermal System dose form. This change affects approximately 160 active drugs.

Qualitative Distinction
Please see the technical documentation for an explanation of Qualitative Distinctions (QDs), which were first release in the August monthly release.

Here are the new concepts with QDs in the September release:

RXCUITTYString
1806380SCDOnce-Daily gabapentin 300 MG Oral Tablet
1115012SBDOnce-Daily gabapentin 300 MG Oral Tablet [Gralise]
1806382SCDOnce-Daily gabapentin 600 MG Oral Tablet
1115013SBDOnce-Daily gabapentin 600 MG Oral Tablet [Gralise]
1806181SCD30/70 Release 24 HR Methylphenidate Hydrochloride 10 MG Extended Release Oral Capsule
1091139SBD30/70 Release 24 HR Methylphenidate Hydrochloride 10 MG Extended Release Oral Capsule [Metadate]
1806187SCD30/70 Release 24 HR Methylphenidate Hydrochloride 20 MG Extended Release Oral Capsule
1091163SBD30/70 Release 24 HR Methylphenidate Hydrochloride 20 MG Extended Release Oral Capsule [Metadate]
1806189SCD30/70 Release 24 HR Methylphenidate Hydrochloride 30 MG Extended Release Oral Capsule
1091178SBD30/70 Release 24 HR Methylphenidate Hydrochloride 30 MG Extended Release Oral Capsule [Metadate]
1806191SCD30/70 Release 24 HR Methylphenidate Hydrochloride 40 MG Extended Release Oral Capsule
1091193SBD30/70 Release 24 HR Methylphenidate Hydrochloride 40 MG Extended Release Oral Capsule [Metadate]
1806193SCD30/70 Release 24 HR Methylphenidate Hydrochloride 50 MG Extended Release Oral Capsule
1091204SBD30/70 Release 24 HR Methylphenidate Hydrochloride 50 MG Extended Release Oral Capsule [Metadate]
1806197SCD30/70 Release 24 HR Methylphenidate Hydrochloride 60 MG Extended Release Oral Capsule
1091220SBD30/70 Release 24 HR Methylphenidate Hydrochloride 60 MG Extended Release Oral Capsule [Metadate]
1806200SCD40/60 Release 24 HR Methylphenidate Hydrochloride 10 MG Extended Release Oral Capsule
1648180SBD40/60 Release 24 HR Methylphenidate Hydrochloride 10 MG Extended Release Oral Capsule [Aptensio]
1806202SCD40/60 Release 24 HR Methylphenidate Hydrochloride 20 MG Extended Release Oral Capsule
1648189SBD40/60 Release 24 HR Methylphenidate Hydrochloride 20 MG Extended Release Oral Capsule [Aptensio]
1806206SCD40/60 Release 24 HR Methylphenidate Hydrochloride 30 MG Extended Release Oral Capsule
1648192SBD40/60 Release 24 HR Methylphenidate Hydrochloride 30 MG Extended Release Oral Capsule [Aptensio]
1806210SCD40/60 Release 24 HR Methylphenidate Hydrochloride 40 MG Extended Release Oral Capsule
1648195SBD40/60 Release 24 HR Methylphenidate Hydrochloride 40 MG Extended Release Oral Capsule [Aptensio]
1806204SCD40/60 Release 24 HR Methylphenidate Hydrochloride 50 MG Extended Release Oral Capsule
1648198SBD40/60 Release 24 HR Methylphenidate Hydrochloride 50 MG Extended Release Oral Capsule [Aptensio]
1806208SCD40/60 Release 24 HR Methylphenidate Hydrochloride 60 MG Extended Release Oral Capsule
1648201SBD40/60 Release 24 HR Methylphenidate Hydrochloride 60 MG Extended Release Oral Capsule [Aptensio]
1806195SCD50/50 Release 24 HR Methylphenidate Hydrochloride 10 MG Extended Release Oral Capsule
1091143SBD50/50 Release 24 HR Methylphenidate Hydrochloride 10 MG Extended Release Oral Capsule [Ritalin]
1806177SCD50/50 Release 24 HR Methylphenidate Hydrochloride 20 MG Extended Release Oral Capsule
1091167SBD50/50 Release 24 HR Methylphenidate Hydrochloride 20 MG Extended Release Oral Capsule [Ritalin]
1806179SCD50/50 Release 24 HR Methylphenidate Hydrochloride 30 MG Extended Release Oral Capsule
1091182SBD50/50 Release 24 HR Methylphenidate Hydrochloride 30 MG Extended Release Oral Capsule [Ritalin]
1806183SCD50/50 Release 24 HR Methylphenidate Hydrochloride 40 MG Extended Release Oral Capsule
1091197SBD50/50 Release 24 HR Methylphenidate Hydrochloride 40 MG Extended Release Oral Capsule [Ritalin]
1806185SCD50/50 Release 24 HR Methylphenidate Hydrochloride 60 MG Extended Release Oral Capsule
1600909SBD50/50 Release 24 HR Methylphenidate Hydrochloride 60 MG Extended Release Oral Capsule [Ritalin]

For each SCD or SBD with a QD, there is an associated attribute in RXNSAT with the attribute name (ATN) of 'RXN_QUALITATIVE_DISTINCTION'. The September release contains the following new attributes to match the QD strings found in the SCD and SBD normalized names:

  • 30/70 Release
  • 40/60 Release
  • 50/50 Release
  • Once-Daily

Data Counts

Term Type or AttributeNumber
Active GPCKs373
Active BPCKs418
Active SCDs18760
Active SBDs10637
Active RXNORM MINs3982
Active RXNORM INs11074
Active RXNORM PINs2580
Active RXNORM BNs6326
Active RXNORM DFs116
  
Obsolete GPCKs142
Obsolete BPCKs128
Obsolete SCDs16216
Obsolete SBDs10129
Obsolete RXNORM MINs0
Obsolete RXNORM INs0
Obsolete RXNORM PINs0
Obsolete RXNORM BNs9569
Obsolete RXNORM DFs56
Editor-suppressed SCDs1523
Editor-suppressed SBDs1299
Source-asserted NDCs1215808
Distinct source-asserted NDCs573010
SAB=RXNORM NDCs218722
Distinct SAB=RXNORM NDCs218722