March Release - 03/06/2017
This release of RxNorm is consistent with the 2016AB UMLS Metathesaurus release. For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm technical documentation.
Sources
The following sources have been updated since the previous RxNorm release:
| Source Name | SAB | Version |
|---|---|---|
| Vaccines Administered | CVX | CVX_2017_02_08 |
| DrugBank | DRUGBANK | DRUGBANK5.0_2017_02_02 |
| Gold Standard Drug Database | GS | GS_2017_02_13 |
| Medi-Span Master Drug Data Base | MDDB | MDDB_2017_02_08 |
| Multum MediSource Lexicon | MMSL | MMSL_2017_02_01 |
| Micromedex RED BOOK | MMX | MMX_2017_02_06 |
| FDA Structured Product Labels | MTHSPL | MTHSPL_2017_02_27 |
| FDB MedKnowledge (formerly NDDF Plus) | NDDF | NDDF_2017_02_08 |
| Veterans Health Administration National Drug File - Reference Terminology | NDFRT | NDFRT_2017_03_06 |
| NDFRT FDASPL relationships | NDFRT_FDASPL | NDFRT_FDASPL_2017_03_06 |
| NDFRT FMTSME relationships | NDFRT_FMTSME | NDFRT_FMTSME_2017_03_06 |
| US Edition of SNOMED CT (drug information) | SNOMEDCT_US | SNOMEDCT_US_2017_01_31 |
| Veterans Health Administration National Drug File | VANDF | VANDF_2017_01_19 |
The following sources have not been updated in this release:
| Source Name | SAB | Version |
|---|---|---|
| Anatomical Therapeutic Chemical Classification System | ATC | ATC_2017 |
| CMS Formulary Reference File | MTHCMSFRF | MTHCMSFRF_2014 |
| Medical Subject Headings (MeSH) | MSH | MSH2017_2016_08_12 |
Data Changes
This release includes many changes to dose forms for injectable products as part of the ongoing prescribable names (TTY=PSN) work. In addition to the changes to those changes, PSNs for the following dose forms are now available:
- Oral Solution
- Oral Suspension
- Powder for Oral Solution
- Powder for Oral Suspension
- Granules for Oral Solution
- Granules for Oral Suspension
- Topical Oil
- Nasal Spray
- Metered Dose Nasal Spray
- Vaginal Tablet
- Toothpaste
New Data Source Included
The National Library of Medicine (NLM) is pleased to announce the addition of a new data source to RxNorm – CVX (Vaccines Administered). The addition of CVX data to RxNorm helps facilitate the electronic exchange of vaccine information in electronic health records. CVX includes both active and inactive vaccines available in the US. CVX codes for inactive vaccines allow electronic transmission of historical immunization records. CVX is maintained and developed by the Centers for Disease Control and Prevention (CDC), National Center of Immunization and Respiratory Diseases (NCIRD).
New Dose Form Added
RxNorm includes a new dose form: Tablet for Oral Suspension. This dose form is defined as a tablet to be reconstituted with diluent prior to administration to form a suspension intended to be taken by mouth. This change affects 12 SBD concepts and their related graphs.
Qualitative Distinction
Please see the technical documentation for an explanation of Qualitative Distinctions (QDs), which were first released in the August monthly release.
To facilitate e-Prescribing of generic epinephrine auto-injector products, we created separate RXCUIs for each product using QDs. Here are the new concepts with QDs in the March release:
| RXCUI | TTY | String |
|---|---|---|
| 727316 | SCD | NDA019430 0.3 ML Epinephrine 0.5 MG/ML Auto-Injector |
| 727386 | SBD | NDA019430 0.3 ML Epinephrine 0.5 MG/ML Auto-Injector [Epipen] |
| 1870207 | SCD | NDA019430 0.3 ML Epinephrine 1 MG/ML Auto-Injector |
| 727347 | SBD | NDA019430 0.3 ML Epinephrine 1 MG/ML Auto-Injector [Epipen] |
| 1870225 | SCD | NDA020800 0.15 ML Epinephrine 1 MG/ML Auto-Injector |
| 891437 | SBD | NDA020800 0.15 ML Epinephrine 1 MG/ML Auto-Injector [Adrenaclick] |
| 1870230 | SCD | NDA020800 0.3 ML Epinephrine 1 MG/ML Auto-Injector |
| 891438 | SBD | NDA020800 0.3 ML Epinephrine 1 MG/ML Auto-Injector [Adrenaclick] |
| 1870232 | SCD | NDA201739 0.15 ML Epinephrine 1 MG/ML Auto-Injector |
| 1305268 | SBD | NDA201739 0.15 ML Epinephrine 1 MG/ML Auto-Injector [Auvi-Q] |
| 1870205 | SCD | NDA201739 0.3 ML Epinephrine 1 MG/ML Auto-Injector |
| 1305269 | SBD | NDA201739 0.3 ML Epinephrine 1 MG/ML Auto-Injector [Auvi-Q] |
For each SCD or SBD with a QD, there is an associated attribute in RXNSAT with the attribute name (ATN) of 'RXN_QUALITATIVE_DISTINCTION'. The March release contains the following new attributes to match the QD strings found in the SCD and SBD normalized names:
- NDA019430
- NDA020800
- NDA201739
Data Counts
| Term Type or Attribute | Number |
|---|---|
| Active GPCKs | 363 |
| Active BPCKs | 425 |
| Active SCDs | 18740 |
| Active SBDs | 10484 |
| Active RXNORM MINs | 3958 |
| Active RXNORM INs | 11284 |
| Active RXNORM PINs | 2633 |
| Active RXNORM BNs | 6128 |
| Active RXNORM DFs | 116 |
| Obsolete GPCKs | 157 |
| Obsolete BPCKs | 137 |
| Obsolete SCDs | 16236 |
| Obsolete SBDs | 10323 |
| Obsolete RXNORM MINs | 0 |
| Obsolete RXNORM INs | 0 |
| Obsolete RXNORM PINs | 0 |
| Obsolete RXNORM BNs | 9823 |
| Obsolete RXNORM DFs | 59 |
| Editor-suppressed SCDs | 1668 |
| Editor-suppressed SBDs | 1332 |
| Source-asserted NDCs | 1250163 |
| Distinct source-asserted NDCs | 591022 |
| SAB=RXNORM NDCs | 224124 |
| Distinct SAB=RXNORM NDCs | 224124 |
Last Reviewed: March 6, 2017