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Unified Medical Language System® (UMLS®)

RxNorm Release Notes

December Release - 12/04/2017

This release of RxNorm is consistent with the 2017AB UMLS Metathesaurus release. For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.

Sources

The following sources have been updated since the previous RxNorm release:

Source NameSABVersion
Vaccines Administered CVX CVX_2017_11_01
DrugBank DRUGBANK DRUGBANK5.0_2017_11_02
Gold Standard Drug Database GS GS_2017_11_09
Multum MediSource Lexicon MMSL MMSL_2017_11_01
Micromedex RED BOOK MMX MMX_2017_11_06
FDA Structured Product Labels MTHSPL MTHSPL_2017_11_24
FDB MedKnowledge (formerly NDDF Plus) NDDF NDDF_2017_11_08
Veterans Health Administration National Drug File VANDF VANDF_2017_11_08

*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions, please contact: medispan-support@wolterskluwer.com.

The following sources have not been updated in this release:

Source NameSABVersion
Anatomical Therapeutic Chemical Classification System ATC ATC_2017
Medical Subject Headings (MeSH) MSH MSH2018_2017_08_11
CMS Formulary Reference File MTHCMSFRF MTHCMSFRF_2014
Veterans Health Administration National Drug File - Reference Terminology NDFRT NDFRT_2017_11_06
NDFRT FDASPL relationships NDFRT_FDASPL NDFRT_FDASPL_2017_11_06
NDFRT FMTSME relationships NDFRT_FMTSME NDFRT_FMTSME_2017_11_06
US Edition of SNOMED CT (drug information) SNOMEDCT_US SNOMEDCT_US_2017_07_31

Data Changes

Database Load Scripts Updated
We upgraded our UTS authentication system recently and subsequently changed the automation scripts. The updated terminology download automation script is now available at: https://download.nlm.nih.gov/rxnorm/terminology_download_script.zip.

RxNorm Representation of FDA’s Nonproprietary Naming of Biological Products
The FDA started adding 4-letter suffixes to the nonproprietary ingredient name of new biological products. The FDA-designated distinguishing suffix is devoid of meaning and composed of four lowercase letters.

RxNorm is representing the nonproprietary ingredient name lacking the 4-letter suffix as an ingredient (TTY=IN). The more granular ingredient name with the 4-letter suffix is represented as a precise ingredient (TTY=PIN). To illustrate, here are several RxNorm forms for the biological product Renflexis:

TTYRXCUIString
SBD 1927290 infliximab-abda 100 MG Injection [Renflexis]
SCD 1927285 infliximab-abda 100 MG Injection
PIN 1927283 infliximab-abda
IN 191831 infliximab

For more information about the FDA’s Nonproprietary Naming of Biological Products, go to: https://www.fda.gov/downloads/drugs/guidances/ucm459987.pdf

Data Counts

Term Type or AttributeNumber
Active GPCKs373
Active BPCKs445
Active SCDs18289
Active SBDs10442
Active RXNORM MINs3962
Active RXNORM INs11530
Active RXNORM PINs2720
Active RXNORM BNs6083
Active RXNORM DFs116
  
Obsolete GPCKs169
Obsolete BPCKs144
Obsolete SCDs16886
Obsolete SBDs10620
Obsolete RXNORM MINs0
Obsolete RXNORM INs0
Obsolete RXNORM PINs0
Obsolete RXNORM BNs9985
Obsolete RXNORM DFs59
Editor-suppressed SCDs1714
Editor-suppressed SBDs1375
SAB=RXNORM NDCs230532
Distinct SAB=RXNORM NDCs230532