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Unified Medical Language System® (UMLS®)

RxNorm Release Notes

March Release - 03/05/2018

This release of RxNorm is consistent with the 2017AB UMLS Metathesaurus release. For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.

Sources

The following source versions in bold have been updated since the previous RxNorm release:

Source NameSABVersion
Anatomical Therapeutic Chemical Classification System ATC ATC_2018
Vaccines Administered CVX CVX_2018_01_18
DrugBank DRUGBANK DRUGBANK5.0_2018_01_29
Gold Standard Drug Database GS GS_2018_01_31
Multum MediSource Lexicon MMSL MMSL_2018_02_01
Micromedex RED BOOK MMX MMX_2018_01_29
Medical Subject Headings (MeSH) MSH MSH2018_2017_08_11
CMS Formulary Reference File MTHCMSFRF MTHCMSFRF_2014
FDA Structured Product Labels MTHSPL MTHSPL_2018_02_23
FDB MedKnowledge (formerly NDDF Plus) NDDF NDDF_2018_01_31
Veterans Health Administration National Drug File - Reference Terminology NDFRT NDFRT_2018_02_05
NDFRT FDASPL relationships NDFRT_FDASPL NDFRT_FDASPL_2018_02_05
NDFRT FMTSME relationships NDFRT_FMTSME NDFRT_FMTSME_2018_02_05
US Edition of SNOMED CT (drug information) SNOMEDCT_US SNOMEDCT_US_2018_01_31
Veterans Health Administration National Drug File VANDF VANDF_2018_01_26

*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions, please contact: medispan-support@wolterskluwer.com.

Data Changes

NDF-RT/MED-RT Reminder
The Veterans Health Administration (VHA) is replacing its National Drug File-Reference Terminology (NDF-RT) with Medication Reference Terminology (MED-RT). The last release of NDF-RT is in the RxNorm full March release and will remain in the RxNorm full monthly releases for the next several months. There are no plans to include MED-RT in RxNorm; however, MED-RT will be included in the UMLS Metathesaurus along with RxNorm and its source vocabularies. The anticipated first release date of MED-RT is Monday, March 5th. For information about the MED-RT release, go to: https://www.cancer.gov/research/resources/terminology/fmt.

New Dose Form
RxNorm includes a new dose form: Oral Tablet with Sensor. This dose form is defined as a tablet taken orally that digitally tracks if patients have ingested their medication.

Here are the concepts using the new dose form Oral Tablet with Sensor in the March release:

RXCUITTYString
1998451 SCD aripiprazole 10 MG Oral Tablet with Sensor
1998453 SBD aripiprazole 10 MG Oral Tablet with Sensor [Abilify]
1998454 SCD aripiprazole 15 MG Oral Tablet with Sensor
1998455 SBD aripiprazole 15 MG Oral Tablet with Sensor [Abilify]
1998456 SCD aripiprazole 2 MG Oral Tablet with Sensor
1998457 SBD aripiprazole 2 MG Oral Tablet with Sensor [Abilify]
1998458 SCD aripiprazole 20 MG Oral Tablet with Sensor
1998459 SBD aripiprazole 20 MG Oral Tablet with Sensor [Abilify]
1998460 SCD aripiprazole 30 MG Oral Tablet with Sensor
1998461 SBD aripiprazole 30 MG Oral Tablet with Sensor [Abilify]
1998462 SCD aripiprazole 5 MG Oral Tablet with Sensor
1998463 SBD aripiprazole 5 MG Oral Tablet with Sensor [Abilify]

Qualitative Distinction
Qualitative Distinction modifiers allow flexibility in the RxNorm model to create new RXCUIs as needed. Please see the technical documentation for more information about Qualitative Distinctions (QDs), which were first released in the August 2016 monthly release.

Here are the new concepts with QDs in the March release:

RXCUITTYString
1998771SCDBreath-Actuated 120 ACTUAT Beclomethasone Dipropionate 0.08 MG/ACTUAT Metered Dose Inhaler
1998772SBDBreath-Actuated 120 ACTUAT Beclomethasone Dipropionate 0.08 MG/ACTUAT Metered Dose Inhaler [Qvar]
1998773SCDBreath-Actuated 120 ACTUAT Beclomethasone Dipropionate 0.04 MG/ACTUAT Metered Dose Inhaler
1998774SBDBreath-Actuated 120 ACTUAT Beclomethasone Dipropionate 0.04 MG/ACTUAT Metered Dose Inhaler [Qvar]

For each SCD or SBD with a QD, there is an associated attribute in RXNSAT with the attribute name (ATN) of 'RXN_QUALITATIVE_DISTINCTION'. The March release contains the following new attribute value (ATV) to match the QD strings found in the SCD and SBD normalized names:

  • Breath-Actuated

New Unit of Measure
RxNorm includes a new unit of measure: SQ-HDM. SQ is a method of standardization of biological potency, major allergen content, and complexity of the allergen extract; HDM is an abbreviation for house dust mite.

Here are the new concepts with the SQ-HDM unit of measure in the March release:

RXCUITTYString
1998624SCDAmerican house dust mite extract 6 SQ-HDM / European house dust mite extract 6 SQ-HDM Sublingual Tablet
1998631SBDAmerican house dust mite extract 6 SQ-HDM / European house dust mite extract 6 SQ-HDM Sublingual Tablet [Odactra]

Data Counts

Term Type or AttributeNumber
Active GPCKs380
Active BPCKs456
Active SCDs18486
Active SBDs10425
Active RXNORM MINs3975
Active RXNORM INs11697
Active RXNORM PINs2743
Active RXNORM BNs6053
Active RXNORM DFs117
  
Obsolete GPCKs166
Obsolete BPCKs143
Obsolete SCDs16811
Obsolete SBDs10712
Obsolete RXNORM MINs0
Obsolete RXNORM INs0
Obsolete RXNORM PINs0
Obsolete RXNORM BNs10034
Obsolete RXNORM DFs59
Editor-suppressed SCDs1749
Editor-suppressed SBDs1399
SAB=RXNORM NDCs238681
Distinct SAB=RXNORM NDCs238681