Skip Navigation Bar
NLM logo

Unified Medical Language System® (UMLS®)

RxNorm Release Notes

April Release - 4/06/2020

This full release of RxNorm is consistent with the 2019AB UMLS Metathesaurus release. For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.


Sources

The following sources with version names in bold have been updated since the previous RxNorm release:

Source NameSABVersion
Vaccines Administered CVX CVX_2020_02_12
DrugBank DRUGBANK DRUGBANK5.0_2020_02_27
Gold Standard Drug Database GS GS_2020_03_26
Multum MediSource Lexicon MMSL MMSL_2020_03_01
Micromedex RED BOOK MMX MMX_2020_03_09
FDA Structured Product Labels MTHSPL MTHSPL_2020_03_28
FDB MedKnowledge (formerly NDDF Plus) NDDF NDDF_2020_04_01
RxNorm normalized names and codes RXNORM RRXNORM_19AB_200406F
Veterans Health Administration National Drug File VANDF VANDF_2020_02_28


The following sources have not been updated since the previous RxNorm release:

Source NameSABVersion
Anatomical Therapeutic Chemical Classification System ATC ATC_2020
Medical Subject Headings (MeSH) MSH MSH2020_2019_08_27
CMS Formulary Reference File MTHCMSFRF MTHCMSFRF_2014
US Edition of SNOMED CT (drug information) SNOMEDCT_US SNOMEDCT_US_2020_01_31
USP Compendial Nomenclature USP USP_2020_02_06

*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact: medispan-support@wolterskluwer.com.


Data Changes

Investigational Drugs in RxNorm

In March 2020, the World Health Organization declared the Coronavirus disease (COVID-19) a pandemic. Because of this significant public health concern, we have reexamined the scope of RxNorm. As a result, the April 2020 release of RxNorm contains the following investigational drug information:

  • Ingredient (IN): remdesivir (RXCUI 2284718); and
  • Semantic Clinical Drug (SCD): remdesivir 100 MG Injection (RXCUI 2284960)

For more information about this RxNorm policy change, see the following NLM Technical Bulletin: https://www.nlm.nih.gov/pubs/techbull/ma20/ma20_rx_norm_investigational_drugs.html

Dose Form Changes

Two new dose forms are available starting with the April 2020 release. The new dose forms are:

  • Delayed Release Oral Granules; and
  • Inhalation Spray

Inhalation Spray and Metered Dose Inhaler are both valid RxNorm dose forms. For certain medications, Inhalation Spray replaced the Metered Dose Inhaler dose form while retaining the same RXCUI. Here are the new prescribable drug names where Inhalation Spray replaced Metered Dose Inhaler:

RXCUITTYString
1190220SCD120 ACTUAT Albuterol 0.1 MG/ACTUAT / Ipratropium Bromide 0.02 MG/ACTUAT Inhalation Spray
1190225SBD120 ACTUAT Albuterol 0.1 MG/ACTUAT / Ipratropium Bromide 0.02 MG/ACTUAT Inhalation Spray [Combivent]
836286SCD200 ACTUAT Albuterol 0.09 MG/ACTUAT / Ipratropium Bromide 0.018 MG/ACTUAT Inhalation Spray
836366SBD200 ACTUAT Albuterol 0.09 MG/ACTUAT / Ipratropium Bromide 0.018 MG/ACTUAT Inhalation Spray [Combivent]
1546077SCD28 ACTUAT olodaterol 0.0025 MG/ACTUAT Inhalation Spray
1546079SBD28 ACTUAT olodaterol 0.0025 MG/ACTUAT Inhalation Spray [Striverdi]
1546082SCD60 ACTUAT olodaterol 0.0025 MG/ACTUAT Inhalation Spray
1546083SBD60 ACTUAT olodaterol 0.0025 MG/ACTUAT Inhalation Spray [Striverdi]
2166203SCD10 ACTUAT tiotropium 0.0025 MG/ACTUAT Inhalation Spray
2166204SBD10 ACTUAT tiotropium 0.0025 MG/ACTUAT Inhalation Spray [Spiriva]
1552008SCD28 ACTUAT tiotropium 0.0025 MG/ACTUAT Inhalation Spray
1552009SBD28 ACTUAT tiotropium 0.0025 MG/ACTUAT Inhalation Spray [Spiriva]
1552002SCD60 ACTUAT tiotropium 0.0025 MG/ACTUAT Inhalation Spray
1552004SBD60 ACTUAT tiotropium 0.0025 MG/ACTUAT Inhalation Spray [Spiriva]
1667885SCD28 ACTUAT tiotropium 0.00125 MG/ACTUAT Inhalation Spray
1667886SBD28 ACTUAT tiotropium 0.00125 MG/ACTUAT Inhalation Spray [Spiriva]
1667880SCD60 ACTUAT tiotropium 0.00125 MG/ACTUAT Inhalation Spray
1667882SBD60 ACTUAT tiotropium 0.00125 MG/ACTUAT Inhalation Spray [Spiriva]
2166927SCD10 ACTUAT olodaterol 0.0025 MG/ACTUAT / tiotropium 0.0025 MG/ACTUAT Inhalation Spray
2166928SBD10 ACTUAT olodaterol 0.0025 MG/ACTUAT / tiotropium 0.0025 MG/ACTUAT Inhalation Spray [Stiolto]
1651266SCD28 ACTUAT olodaterol 0.0025 MG/ACTUAT / tiotropium 0.0025 MG/ACTUAT Inhalation Spray
1651271SBD28 ACTUAT olodaterol 0.0025 MG/ACTUAT / tiotropium 0.0025 MG/ACTUAT Inhalation Spray [Stiolto]
1651274SCD60 ACTUAT olodaterol 0.0025 MG/ACTUAT / tiotropium 0.0025 MG/ACTUAT Inhalation Spray
1651275SBD60 ACTUAT olodaterol 0.0025 MG/ACTUAT / tiotropium 0.0025 MG/ACTUAT Inhalation Spray [Stiolto]

Data Counts

Term Type or AttributeNumber
Active GPCKs439
Active BPCKs522
Active SCDs17265
Active SBDs9949
Active RXNORM MINs3742
Active RXNORM INs12500
Active RXNORM PINs2962
Active RXNORM BNs5581
Active RXNORM DFs121
  
Obsolete GPCKs208
Obsolete BPCKs185
Obsolete SCDs17562
Obsolete SBDs11139
Obsolete RXNORM MINs0
Obsolete RXNORM INs0
Obsolete RXNORM PINs0
Obsolete RXNORM BNs6343
Obsolete RXNORM DFs62
Editor-suppressed SCDs1756
Editor-suppressed SBDs1479
SAB=RXNORM NDCs238628
Distinct SAB=RXNORM NDCs238628

Last Reviewed: April 9, 2020