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Unified Medical Language System® (UMLS®)

RxNorm Release Notes

July Release - 7/06/2020

This full release of RxNorm is consistent with the 2020AA UMLS Metathesaurus release. For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.


Sources

The following sources with version names in bold have been updated since the previous RxNorm release:

Source NameSABVersion
DrugBank DRUGBANK DRUGBANK5.0_2020_06_01
Gold Standard Drug Database GS GS_2020_06_11
Multum MediSource Lexicon MMSL MMSL_2020_06_01
Micromedex RED BOOK MMX MMX_2020_06_01
FDA Structured Product Labels MTHSPL MTHSPL_2020_06_26
FDB MedKnowledge (formerly NDDF Plus) NDDF NDDF_2020_06_10
RxNorm normalized names and codes RXNORM RXNORM_20AA_200706F
Veterans Health Administration National Drug File VANDF VANDF_2020_05_31


The following sources have not been updated since the previous RxNorm release:

Source NameSABVersion
Anatomical Therapeutic Chemical Classification System ATC ATC_2020
Vaccines Administered CVX CVX_2020_05_11
Medical Subject Headings (MeSH) MSH MSH2020_2020_01_15
CMS Formulary Reference File MTHCMSFRF MTHCMSFRF_2014
US Edition of SNOMED CT (drug information) SNOMEDCT_US SNOMEDCT_US_2020_01_31
USP Compendial Nomenclature USP USP_2020_02_06

*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact: medispan-support@wolterskluwer.com.


Data Changes

New NHRIC Attribute in RXNSAT.RRF for MTHSPL  

National Health Related Item Code (NHRIC) values are now identified separately from National Drug Code (NDC) values for the FDA Structured Product Labeling (MTHSPL) data source in the RxNorm data set.  The attribute name (ATN) in the RXNSAT.RRF file is NHRIC where the source abbreviation (SAB) is MTHSPL. This change is for SAB=MTHSPL only. Note that an ATN=NHRIC for SAB=RXNORM will not exist. Approximately 640 values are impacted in the RXNSAT.RRF file.  

 

New Dose Form

The July 2020 release includes the new dose form: Powder for Pyelocalyceal Solution.
Here are the new prescribable drug names with the new dose form Powder for Pyelocalyceal Solution.

RXCUI               TTY       STRING

2375818          SCD      mitomycin 40 MG Powder for Pyelocalyceal Solution

2375823          SBD      mitomycin 40 MG Powder for Pyelocalyceal Solution [Jelmyto]

 

Representing Multi-Ingredient Biological Products

For multi-ingredient biological products, the suffix will be added to each active ingredient. An ingredient with a suffix will be a precise ingredient (PIN) to its appropriate base ingredient (IN) atom.
Here are the new prescribable drug names for combination biological products:

RXCUI               TTY       STRING

2119714          SCD          5 ML hyaluronidase-oysk 2000 UNT/ML / trastuzumab-oysk 120 MG/ML Injection

2119719          SBD          5 ML hyaluronidase-oysk 2000 UNT/ML / trastuzumab-oysk 120 MG/ML Injection [Herceptin Hylecta]

2375136          SCD       15 ML daratumumab-fihj 120 MG/ML / hyaluronidase-fihj 2000 UNT/ML Injection

2375141          SBD       15 ML daratumumab-fihj 120 MG/ML / hyaluronidase-fihj 2000 UNT/ML Injection [Darzalex Faspro]  

 

Continued Reduction in Active National Drug Codes (NDCs)

RxNorm continues to improve the quality of NDC data by identifying NDCs that are no longer active. Users will likely see a reduction in approximately 1,125 live NDCs in the July release. The SUPPRESS value for these NDCs in the RXNSAT.RRF file will change from SUPPRESS = ‘N’ to SUPPRESS = ‘Y’ compared to last month’s release.

 

Notice of Upcoming Data Changes

As a courtesy to users, this section provides advance notice of possible upcoming RxNorm data changes. More information about each change will be provided or repeated in the future. Please note that planned data changes and timelines may change if issues arise.

  • Basis of Strength (BoSS) attributes will change in late 2020/early 2021
    • Several of the BoSS attributes will change from being present on the SCDC to the SCD
  • New RxNorm Terminology Term Types (TTYs) will be added in late 2020/early 2021
    • RxNorm will add three new TTYs:
      • Semantic Clinical Drug Form Precise (SCDFP)
      • Semantic Clinical Dose Form Group Precise (SCDGP)
      • Semantic Branded Drug Form Precise (SBDFP)


Data Counts

Term Type or AttributeNumber
Active GPCKs424
Active BPCKs510
Active SCDs16657
Active SBDs9541
Active RXNORM MINs3724
Active RXNORM INs12756
Active RXNORM PINs2995
Active RXNORM BNs5261
Active RXNORM DFs122
  
Obsolete GPCKs230
Obsolete BPCKs199
Obsolete SCDs18198
Obsolete SBDs11587
Obsolete RXNORM MINs0
Obsolete RXNORM INs0
Obsolete RXNORM PINs0
Obsolete RXNORM BNs6649
Obsolete RXNORM DFs62
Editor-suppressed SCDs1758
Editor-suppressed SBDs1463
SAB=RXNORM NDCs228486
Distinct SAB=RXNORM NDCs228486

Last Reviewed: July 6, 2020