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Unified Medical Language System® (UMLS®)

RxNorm Release Notes

October Release - 10/05/2020

This full release of RxNorm is consistent with the 2020AA UMLS Metathesaurus release. For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.


The following sources with version names in bold have been updated since the previous RxNorm release:

Source NameSABVersion
Vaccines Administered CVX CVX_2020_08_27
DrugBank DRUGBANK DRUGBANK5.0_2020_09_03
Gold Standard Drug Database GS GS_2020_09_14
Multum MediSource Lexicon MMSL MMSL_2020_09_01
Micromedex RED BOOK MMX MMX_2020_09_14
CMS Formulary Reference File MTHCMSFRF MTHCMSFRF_2020
FDA Structured Product Labels MTHSPL MTHSPL_2020_09_25
FDB MedKnowledge (formerly NDDF Plus) NDDF NDDF_2020_09_16
RxNorm normalized names and codes RXNORM RXNORM_20AA_201005F
Veterans Health Administration National Drug File VANDF VANDF_2020_09_01

The following sources have not been updated since the previous RxNorm release:

Source NameSABVersion
Anatomical Therapeutic Chemical Classification System ATC ATC_2020
Medical Subject Headings (MeSH) MSH MSH2020_2020_01_15
US Edition of SNOMED CT (drug information) SNOMEDCT_US SNOMEDCT_US_2020_07_31
USP Compendial Nomenclature USP USP_2020_02_06

*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact:

Data Changes

Remdesivir NDCs Reassigned from Generic to Branded Drug Names

Since April 2020, the National Drug Codes (NDCs) 61958290101 and 61958290201 have been associated with generic remdesivir-related Semantic Clinical Drug (SCD) names. Beginning with the October 2020 release, the NDCs will be associated with the brand name Veklury in new Semantic Branded Drug (SBD) names.

Below is a summary of the remdesivir NDC changes in RxNorm.

NDC 61958290101 is moving:

  • From the SCD remdesivir 100 MG Injection (RXCUI 2284960)
  • To the SBD remdesivir 100 MG Injection [Veklury] (RXCUI 2395502)

NDC 61958290201 is moving:

  • From the SCD 20 ML remdesivir 5 MG/ML Injection (RXCUI 2367758)
  • To the SBD 20 ML remdesivir 5 MG/ML Injection [Veklury] (RXCUI 2395504)

Regiocit Added to RxNorm for Emergency Use

Regiocit, a drug allowed under the U.S. Food & Drug Administration Emergency Use Authorization (EUA), became available in the RxNorm September 30, 2020 weekly releases on the RxNorm Files page. The name is also included in the RxNorm October 2020 Monthly releases.

Regiocit related names and codes included in RxNorm are:

  • SCD: 5000 ML sodium chloride 5.03 MG/ML / sodium citrate 5.29 MG/ML Injection (RXCUI 2397251)
  • SBD: 5000 ML sodium chloride 5.03 MG/ML / sodium citrate 5.29 MG/ML Injection [Regiocit] (RXCUI 2397257)

Below are links for additional information.


Notice of Upcoming RxNorm Data Changes

As a courtesy to users, this section provides advance notice of possible upcoming RxNorm data changes. More information about each change will be provided or repeated in the future. Please note that planned data changes and timelines may change if issues arise.

  • REMINDER: Deleting UMLS Metathesaurus UMLSAUI & UMLSCUI in the RxNorm November 2020 Monthly Release
    • The Unified Medical Language System (UMLS) atom unique identifier (AUI) and concept unique identifier (CUI) will not exist in RxNorm beginning with the November 2020 release. In other words, the UMLSAUI and UMLSCUI attributes will be deleted from the RxNorm terminology in the RXNSAT.RRF file. Users can obtain the UMLSAUI and UMLSCUI directly from the Metathesaurus if needed.

Data Counts

Term Type or AttributeNumber
Active GPCKs430
Active BPCKs514
Active SCDs16818
Active SBDs9443
Active RXNORM MINs3733
Active RXNORM INs12969
Active RXNORM PINs3040
Active RXNORM BNs5144
Active RXNORM DFs121
Obsolete GPCKs231
Obsolete BPCKs197
Obsolete SCDs18218
Obsolete SBDs10703
Obsolete RXNORM MINs0
Obsolete RXNORM INs0
Obsolete RXNORM PINs0
Obsolete RXNORM BNs6101
Obsolete RXNORM DFs63
Editor-suppressed SCDs1782
Editor-suppressed SBDs1470
Distinct SAB=RXNORM NDCs244376

Last Reviewed: October 5, 2020