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Unified Medical Language System® (UMLS®)

RxNorm Release Notes

November Release - 11/02/2020

For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.


Sources

The following sources with version names in bold have been updated since the previous RxNorm release:

Source NameSABVersion
DrugBank DRUGBANK DRUGBANK5.0_2020_10_01
Gold Standard Drug Database GS GS_2020_10_08
Multum MediSource Lexicon MMSL MMSL_2020_10_01
Micromedex RED BOOK MMX MMX_2020_10_12
Medical Subject Headings (MeSH) MSH MSH2020_2020_07_16
FDA Structured Product Labels MTHSPL MTHSPL_2020_10_23
FDB MedKnowledge (formerly NDDF Plus) NDDF NDDF_2020_10_07
RxNorm normalized names and codes RXNORM RXNORM_20AA_201102F
Veterans Health Administration National Drug File VANDF VANDF_2020_10_01


The following sources have not been updated since the previous RxNorm release:

Source NameSABVersion
Anatomical Therapeutic Chemical Classification System ATC ATC_2020
Vaccines Administered CVX CVX_2020_08_27
CMS Formulary Reference File MTHCMSFRF MTHCMSFRF_2020
US Edition of SNOMED CT (drug information) SNOMEDCT_US SNOMEDCT_US_2020_07_31
USP Compendial Nomenclature USP USP_2020_02_06

*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact: medispan-support@wolterskluwer.com.


Data Changes


Remdesivir NDC Changes

The remdesivir National Drug Code (NDC) changes announced for the October 2020 release will be reversed. The NDCs 61958290101 and 61958290201 will be associated with generic remdesivir-related Semantic Clinical Drug (SCD) names. Also, the branded drug Veklury will have new NDCs, specifically 61958290102 & 61958290202.


Below is a summary of the remdesivir-related product names, RxNorm Concept Unique Identifiers (RXCUIs), and NDCs in the RxNorm November 2020 release.

SCD: remdesivir 100 MG Injection

  • RXCUI: 2284960
  • NDC: 61958290101

SCD: 20 ML remdesivir 5 MG/ML Injection

  • RXCUI 2367758
  • NDC: 61958290201

SBD: remdesivir 100 MG Injection [Veklury]

  • RXCUI: 2395502
  • NDC: 61958290102

SBD: 20 ML remdesivir 5 MG/ML Injection [Veklury]

  • RXCUI 2367758
  • NDC: 61958290202

UMLS Metathesaurus Data No Longer Updated in RxNorm

The Unified Medical Language System (UMLS) Metathesaurus data in RxNorm will no longer be updated beginning with the November 2020 release. In other words, the UMLS atom unique identifier (UMLSAUI) and UMLS concept unique identifier (UMLSCUI) attributes will be frozen with the UMLS 2020AA release values in the RXNSAT.RRF file. Users can obtain current UMLS AUIs and UMLS CUIs directly from the Metathesaurus if needed. The UMLSCUI and UMLSAUI are expected to be deleted in the RxNorm December 2020 release (see below).


Also, the UMLS Metathesaurus version information will be frozen with the year 2020 while the RxNorm version dates will continue to change for several data values in the RxNorm terminology (SAB=RXNORM). Below are the impacted data values.


Notice of Upcoming RxNorm Data Changes

As a courtesy to users, this section provides advance notice of possible upcoming RxNorm data changes. More information about each change will be provided or repeated in the future. Please note that planned data changes and timelines may change if issues arise.

  • CORRECTION: UMLSAUI & UMLSCUI Attributes will be Deleted in the RxNorm December 2020 Release
    • The UMLSAUI and UMLSCUI are expected to be deleted from RxNorm beginning with the December 2020 release, rather than the November 2020 release as previously announced. Users can obtain the UMLSAUI and UMLSCUI directly from the Metathesaurus if needed.

Data Counts

Term Type or AttributeNumber
Active GPCKs431
Active BPCKs515
Active SCDs16851
Active SBDs9420
Active RXNORM MINs3734
Active RXNORM INs13012
Active RXNORM PINs3050
Active RXNORM BNs5120
Active RXNORM DFs121
  
Obsolete GPCKs229
Obsolete BPCKs196
Obsolete SCDs18229
Obsolete SBDs10708
Obsolete RXNORM MINs0
Obsolete RXNORM INs0
Obsolete RXNORM PINs0
Obsolete RXNORM BNs6096
Obsolete RXNORM DFs63
Editor-suppressed SCDs1788
Editor-suppressed SBDs1478
SAB=RXNORM NDCs245820
Distinct SAB=RXNORM NDCs245820

Last Reviewed: November 2, 2020