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Unified Medical Language System® (UMLS®)

RxNorm Release Notes

February Release - 02/01/2021

For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.


The following sources with version names in bold have been updated since the previous RxNorm release:

Source NameSABVersion
Anatomical Therapeutic Chemical Classification System ATC ATC_2021
Vaccines Administered CVX CVX_2021_01_12
DrugBank DRUGBANK DRUGBANK5.0_2021_01_04
Gold Standard Drug Database GS GS_2021_01_11
Multum MediSource Lexicon MMSL MMSL_2020_01_01
Micromedex RED BOOK MMX MMX_2021_01_11
FDA Structured Product Labels MTHSPL MTHSPL_2021_01_22
FDB MedKnowledge (formerly NDDF Plus) NDDF NDDF_2021_01_13
RxNorm normalized names and codes RXNORM RXNORM_20AA_210201F
USP Compendial Nomenclature USP USP_2021_01_15
Veterans Health Administration National Drug File VANDF VANDF_2020_12_31

The following sources have not been updated since the previous RxNorm release:

Source NameSABVersion
Medical Subject Headings (MeSH) MSH MSH2021_2020_07_16
CMS Formulary Reference File MTHCMSFRF MTHCMSFRF_2020
US Edition of SNOMED CT (drug information) SNOMEDCT_US SNOMEDCT_US_2020_07_31

*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact:


No major changes to report for the February release.


As a courtesy to users, this section provides advance notice of possible upcoming RxNorm data changes. More information about each change will be provided or repeated in the future. Please note that planned data changes and timelines may change if issues arise.

Basis of Strength (BoSS) attributes will change in April 2021 at the earliest

  • Several of the BoSS attributes will change from being present on the SCDC to the SCD

New RxNorm terminology Term Types (TTYs) will be added April 2021 at the earliest

  • RxNorm will add three new TTYs:
    • Semantic Clinical Drug Form Precise (SCDFP)
    • Semantic Clinical Dose Form Group Precise (SCDGP)
    • Semantic Branded Drug Form Precise (SBDFP)

Two RxNorm weekly releases returning

  • In 2019, RxNorm discontinued 2 weekly releases. They will return and will be available on April 28, 2021 and October 27, 2021. The two returning weekly releases will immediately precede the full May and November RxNorm monthly releases moving forward. RxNorm will create 52 weekly releases per year.


Historical Code Analysis using RxNorm API

Did you know that historical codes, such as obsolete NDCs and RXCUIs can be analyzed with the RxNorm API? For example, see /ndcstatus and /rxcui/{rxcui}/historystatus resources among others on the RxNorm API page for more information:

Data Counts

Term Type or AttributeNumber
Active GPCKs431
Active BPCKs517
Active SCDs16924
Active SBDs9436
Active RXNORM MINs3736
Active RXNORM INs13168
Active RXNORM PINs3083
Active RXNORM BNs5136
Active RXNORM DFs121
Obsolete GPCKs232
Obsolete BPCKs199
Obsolete SCDs18256
Obsolete SBDs10733
Obsolete RXNORM MINs0
Obsolete RXNORM INs0
Obsolete RXNORM PINs0
Obsolete RXNORM BNs6093
Obsolete RXNORM DFs63
Editor-suppressed SCDs1798
Editor-suppressed SBDs1483
Distinct SAB=RXNORM NDCs250503

Last Reviewed: February 1, 2021