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Unified Medical Language System® (UMLS®)

RxNorm Release Notes

May Release - 05/03/2021

For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.


The following sources with version names in bold have been updated since the previous RxNorm release:

Source NameSABVersion
Vaccines Administered CVX CVX_2021_04_09
DrugBank DRUGBANK DRUGBANK5.0_2021_04_01
Gold Standard Drug Database GS GS_2021_04_08
Multum MediSource Lexicon MMSL MMSL_2021_04_01
Micromedex RED BOOK MMX MMX_2021_04_05
FDA Structured Product Labels MTHSPL MTHSPL_2021_04_23
FDB MedKnowledge (formerly NDDF Plus) NDDF NDDF_2021_04_07
RxNorm normalized names and codes RXNORM RXNORM_20AA_210503F
USP Compendial Nomenclature USP USP_2021_04_15
Veterans Health Administration National Drug File VANDF VANDF_2021_03_31

The following sources have not been updated since the previous RxNorm release:

Source NameSABVersion
Anatomical Therapeutic Chemical Classification System ATC ATC_2021
Medical Subject Headings (MeSH) MSH MSH2021_2021_01_25
CMS Formulary Reference File MTHCMSFRF MTHCMSFRF_2020
US Edition of SNOMED CT (drug information) SNOMEDCT_US SNOMEDCT_US_2021_01_31

*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact:


No major changes to report for the May 2021 release.


As a courtesy to users, this section provides advance notice of possible upcoming RxNorm data changes. More information about each change will be provided or repeated in the future. Please note that planned data changes and timelines may change if issues arise.

BoSS attribute changes and RxNorm Terminology Term Type changes have been delayed.

  • Basis of Strength (BoSS) Attributes Changing in September 2021 at the Earliest
    • Several of the BoSS attributes will change from being present on the SCDC to the SCD
  • New RxNorm Terminology Term Types (TTYs) will be Added Late Fall/Early Winter 2021 at the Earliest
    • RxNorm will add three new TTYs:
      • Semantic Clinical Drug Form Precise (SCDFP)
      • Semantic Clinical Dose Form Group Precise (SCDGP)
      • Semantic Branded Drug Form Precise (SBDFP)

Data Counts

Term Type or AttributeNumber
Active GPCKs438
Active BPCKs522
Active SCDs16521
Active SBDs9478
Active RXNORM MINs3742
Active RXNORM INs13344
Active RXNORM PINs3110
Active RXNORM BNs5157
Active RXNORM DFs121
Obsolete GPCKs236
Obsolete BPCKs203
Obsolete SCDs18803
Obsolete SBDs10790
Obsolete RXNORM MINs0
Obsolete RXNORM INs0
Obsolete RXNORM PINs0
Obsolete RXNORM BNs6104
Obsolete RXNORM DFs63
Editor-suppressed SCDs1817
Editor-suppressed SBDs1497
Distinct SAB=RXNORM NDCs251485

Last Reviewed: May 3, 2021