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Unified Medical Language System® (UMLS®)

RxNorm Release Notes

June Release - 06/07/2021

For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.


The following sources with version names in bold have been updated since the previous RxNorm release:

Source NameSABVersion
Vaccines Administered CVX CVX_2021_05_20
DrugBank DRUGBANK DRUGBANK5.0_2021_04_30
Gold Standard Drug Database GS GS_2021_05_11
Multum MediSource Lexicon MMSL MMSL_2021_05_01
Micromedex RED BOOK MMX MMX_2021_05_10
FDA Structured Product Labels MTHSPL MTHSPL_2021_05_28
FDB MedKnowledge (formerly NDDF Plus) NDDF NDDF_2021_05_12
RxNorm normalized names and codes RXNORM RXNORM_20AA_210607F
USP Compendial Nomenclature USP USP_2021_04_15
Veterans Health Administration National Drug File VANDF VANDF_2021_04_30

The following sources have not been updated since the previous RxNorm release:

Source NameSABVersion
Anatomical Therapeutic Chemical Classification System ATC ATC_2021
Medical Subject Headings (MeSH) MSH MSH2021_2021_01_25
CMS Formulary Reference File MTHCMSFRF MTHCMSFRF_2020
US Edition of SNOMED CT (drug information) SNOMEDCT_US SNOMEDCT_US_2021_01_31

*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact:


No major changes to report for the June 2021 release.


Did you know RxMix has a pre-built workflow that finds an ATC drug class from a National Drug Code (NDC)? See the RxMix Tutorial page to learn more about RxMix.

Data Counts

Term Type or AttributeNumber
Active GPCKs442
Active BPCKs527
Active SCDs17034
Active SBDs9473
Active RXNORM MINs3744
Active RXNORM INs13386
Active RXNORM PINs3115
Active RXNORM BNs5149
Active RXNORM DFs121
Obsolete GPCKs239
Obsolete BPCKs205
Obsolete SCDs18324
Obsolete SBDs10812
Obsolete RXNORM MINs0
Obsolete RXNORM INs0
Obsolete RXNORM PINs0
Obsolete RXNORM BNs6111
Obsolete RXNORM DFs63
Editor-suppressed SCDs1821
Editor-suppressed SBDs1500
Distinct SAB=RXNORM NDCs254549

Last Reviewed: June 7, 2021