January Release - 01/03/2022
For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.
Sources
The following sources with version names in bold have been updated since the previous RxNorm release:
| Source Name | SAB | Version |
|---|---|---|
| DrugBank | DRUGBANK | DRUGBANK5.0_2021_12_03 |
| Gold Standard Drug Database | GS | GS_2021_12_09 |
| Multum MediSource Lexicon | MMSL | MMSL_2021_12_01 |
| Micromedex RED BOOK | MMX | MMX_2021_12_13 |
| FDA Structured Product Labels | MTHSPL | MTHSPL_2021_12_24 |
| FDB MedKnowledge (formerly NDDF Plus) | NDDF | NDDF_2021_12_15 |
| RxNorm normalized names and codes | RXNORM | RXNORM_20AA_220103F |
| USP Compendial Nomenclature | USP | USP_2021_12_15 |
| Veterans Health Administration National Drug File | VANDF | VANDF_2021_11_30 |
The following sources have not been updated since the previous RxNorm release:
| Source Name | SAB | Version |
|---|---|---|
| Anatomical Therapeutic Chemical Classification System | ATC | ATC_2021 |
| Vaccines Administered | CVX | CVX_2021_11_19 |
| CMS Formulary Reference File | MTHCMSFRF | MTHCMSFRF_2020 |
| Medical Subject Headings (MeSH) | MSH | MSH2022_2021_07_20 |
| US Edition of SNOMED CT (drug information) | SNOMEDCT_US | SNOMEDCT_US_2021_07_31 |
*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact: medispan-support@wolterskluwer.com.
RXNORM DATA CHANGES
Added Evusheld, Paxlovid & molnupiravir COVID-19 Related Medications
The FDA recently issued Emergency Use Authorization (EUA) for AstraZeneca's Evusheld, Pfizer's Paxlovid, and Merck's molnupiravir which are included in the RxNorm January 2022 monthly releases.
Evusheld is a prophylactic medication for COVID-19 for certain adults and pediatric individuals and contains the antibodies tixagevimab co-packaged with cilgavimab which are administered together. Paxlovid and molnupiravir are oral pills that treat COVID-19 disease. Both can be used in adults. Paxlovid can also be used in certain children over 12 years of age.
Here are the new COVID-19 related concepts in RxNorm:
| RXCUI | TTY | RxNorm Name |
|---|---|---|
| 2587313 | BPCK | {1 (1.5 ML cilgavimab 100 MG/ML Injection) / 1 (1.5 ML tixagevimab 100 MG/ML Injection) } Pack [Evusheld 2 vial carton] |
| 2587312 | GPCK | {1 (1.5 ML cilgavimab 100 MG/ML Injection) / 1 (1.5 ML tixagevimab 100 MG/ML Injection) } Pack |
| 2587899 | BPCK | {20 (nirmatrelvir 150 MG Oral Tablet) / 10 (ritonavir 100 MG Oral Tablet) } Pack [Paxlovid 5-Day] |
| 2587898 | GPCK | {20 (nirmatrelvir 150 MG Oral Tablet) / 10 (ritonavir 100 MG Oral Tablet) } Pack |
| 2587906 | SCD | molnupiravir 200 MG Oral Capsule |
Get more information about Emergency Use Authorization (EUA) from the FDA
Get more information about RxNorm's policy change on investigational drugs from NLM
Data Counts
| Term Type or Attribute | Number |
|---|---|
| Active GPCKs | 456 |
| Active BPCKs | 530 |
| Active SCDs | 17143 |
| Active SBDs | 9479 |
| Active RXNORM MINs | 3767 |
| Active RXNORM INs | 13569 |
| Active RXNORM PINs | 3221 |
| Active RXNORM BNs | 5133 |
| Active RXNORM DFs | 121 |
| Obsolete GPCKs | 243 |
| Obsolete BPCKs | 212 |
| Obsolete SCDs | 18555 |
| Obsolete SBDs | 11012 |
| Obsolete RXNORM MINs | 0 |
| Obsolete RXNORM INs | 0 |
| Obsolete RXNORM PINs | 0 |
| Obsolete RXNORM BNs | 6213 |
| Obsolete RXNORM DFs | 63 |
| Editor-suppressed SCDs | 1858 |
| Editor-suppressed SBDs | 1535 |
| SAB=RXNORM NDCs | 260008 |
| Distinct SAB=RXNORM NDCs | 260008 |
Last Reviewed: January 3, 2022