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Unified Medical Language System® (UMLS®)

RxNorm Release Notes

January Release - 01/03/2022

For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.

Sources

The following sources with version names in bold have been updated since the previous RxNorm release:

Source NameSABVersion
DrugBank DRUGBANK DRUGBANK5.0_2021_12_03
Gold Standard Drug Database GS GS_2021_12_09
Multum MediSource Lexicon MMSL MMSL_2021_12_01
Micromedex RED BOOK MMX MMX_2021_12_13
FDA Structured Product Labels MTHSPL MTHSPL_2021_12_24
FDB MedKnowledge (formerly NDDF Plus) NDDF NDDF_2021_12_15
RxNorm normalized names and codes RXNORM RXNORM_20AA_220103F
USP Compendial Nomenclature USP USP_2021_12_15
Veterans Health Administration National Drug File VANDF VANDF_2021_11_30


The following sources have not been updated since the previous RxNorm release:

Source NameSABVersion
Anatomical Therapeutic Chemical Classification System ATC ATC_2021
Vaccines Administered CVX CVX_2021_11_19
CMS Formulary Reference File MTHCMSFRF MTHCMSFRF_2020
Medical Subject Headings (MeSH) MSH MSH2022_2021_07_20
US Edition of SNOMED CT (drug information) SNOMEDCT_US SNOMEDCT_US_2021_07_31

*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact: medispan-support@wolterskluwer.com.


RXNORM DATA CHANGES

Added Evusheld, Paxlovid & molnupiravir COVID-19 Related Medications

The FDA recently issued Emergency Use Authorization (EUA) for AstraZeneca's Evusheld, Pfizer's Paxlovid, and Merck's molnupiravir which are included in the RxNorm January 2022 monthly releases.

Evusheld is a prophylactic medication for COVID-19 for certain adults and pediatric individuals and contains the antibodies tixagevimab co-packaged with cilgavimab which are administered together. Paxlovid and molnupiravir are oral pills that treat COVID-19 disease. Both can be used in adults. Paxlovid can also be used in certain children over 12 years of age.

Here are the new COVID-19 related concepts in RxNorm:

RXCUI TTY RxNorm Name
2587313 BPCK {1 (1.5 ML cilgavimab 100 MG/ML Injection) / 1 (1.5 ML tixagevimab 100 MG/ML Injection) } Pack [Evusheld 2 vial carton]
2587312 GPCK {1 (1.5 ML cilgavimab 100 MG/ML Injection) / 1 (1.5 ML tixagevimab 100 MG/ML Injection) } Pack
2587899 BPCK {20 (nirmatrelvir 150 MG Oral Tablet) / 10 (ritonavir 100 MG Oral Tablet) } Pack [Paxlovid 5-Day]
2587898 GPCK {20 (nirmatrelvir 150 MG Oral Tablet) / 10 (ritonavir 100 MG Oral Tablet) } Pack
2587906 SCD molnupiravir 200 MG Oral Capsule

Get more information about Emergency Use Authorization (EUA) from the FDA
Get more information about RxNorm's policy change on investigational drugs from NLM


Data Counts

Term Type or AttributeNumber
Active GPCKs456
Active BPCKs530
Active SCDs17143
Active SBDs9479
Active RXNORM MINs3767
Active RXNORM INs13569
Active RXNORM PINs3221
Active RXNORM BNs5133
Active RXNORM DFs121
  
Obsolete GPCKs243
Obsolete BPCKs212
Obsolete SCDs18555
Obsolete SBDs11012
Obsolete RXNORM MINs0
Obsolete RXNORM INs0
Obsolete RXNORM PINs0
Obsolete RXNORM BNs6213
Obsolete RXNORM DFs63
Editor-suppressed SCDs1858
Editor-suppressed SBDs1535
SAB=RXNORM NDCs260008
Distinct SAB=RXNORM NDCs260008

Last Reviewed: January 3, 2022