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RxNorm Release Notes

February Release - 02/07/2022

For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.


The following sources with version names in bold have been updated since the previous RxNorm release:

Source NameSABVersion
Vaccines Administered CVX CVX_2022_01_25
DrugBank DRUGBANK DRUGBANK5.0_2022_01_03
Gold Standard Drug Database GS GS_2022_01_10
Multum MediSource Lexicon MMSL MMSL_2022_01_01
Micromedex RED BOOK MMX MMX_2022_01_10
FDA Structured Product Labels MTHSPL MTHSPL_2022_01_28
FDB MedKnowledge (formerly NDDF Plus) NDDF NDDF_2022_01_12
RxNorm normalized names and codes RXNORM RXNORM_20AA_220207F
Veterans Health Administration National Drug File VANDF VANDF_2021_12_31

The following sources have not been updated since the previous RxNorm release:

Source NameSABVersion
Anatomical Therapeutic Chemical Classification System ATC ATC_2021
Medical Subject Headings (MeSH) MSH MSH2022_2021_07_20
CMS Formulary Reference File MTHCMSFRF MTHCMSFRF_2020
US Edition of SNOMED CT (drug information) SNOMEDCT_US SNOMEDCT_US_2021_07_31
USP Compendial Nomenclature USP USP_2021_12_15

*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact:

RxNorm Data Changes

Decrease in Active National Drug Codes (NDCs)

The RxNorm Full February 2022 release contains approximately 23,500 less NDCs in active status compared to last month's RxNorm Full January release. This change is a result of information from the U.S. Food and Drug Administration (FDA). Many of the impacted NDCs are associated with hand sanitizer products.

Related News

Did you know that the RxNav browser removed the "Pill Images" tab in anticipation of the sunset of NLM's RxImage API? All RxImage and Pillbox data are available for download here:

Data Counts

Term Type or AttributeNumber
Active GPCKs451
Active BPCKs527
Active SCDs17035
Active SBDs9419
Active RXNORM MINs3767
Active RXNORM INs13589
Active RXNORM PINs3242
Active RXNORM BNs5094
Active RXNORM DFs121
Obsolete GPCKs248
Obsolete BPCKs215
Obsolete SCDs18694
Obsolete SBDs11095
Obsolete RXNORM MINs0
Obsolete RXNORM INs0
Obsolete RXNORM PINs0
Obsolete RXNORM BNs6266
Obsolete RXNORM DFs63
Editor-suppressed SCDs1861
Editor-suppressed SBDs1537
Distinct SAB=RXNORM NDCs236364

Last Reviewed: February 7, 2022