Skip Navigation Bar
NLM logo

Unified Medical Language System® (UMLS®)

RxNorm Release Notes

March Release - 03/07/2022

For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.


The following sources with version names in bold have been updated since the previous RxNorm release:

Source NameSABVersion
Vaccines Administered CVX CVX_2022_02_14
DrugBank DRUGBANK DRUGBANK5.0_2022_02_03
Gold Standard Drug Database GS GS_2022_02_09
Multum MediSource Lexicon MMSL MMSL_2022_02_01
Micromedex RED BOOK MMX MMX_2022_02_07
FDA Structured Product Labels MTHSPL MTHSPL_2022_02_25
FDB MedKnowledge (formerly NDDF Plus) NDDF NDDF_2022_02_09
RxNorm normalized names and codes RXNORM RXNORM_20AA_220307F
US Edition of SNOMED CT (drug information) SNOMEDCT_US SNOMEDCT_US_2022_01_31
USP Compendial Nomenclature USP USP_2022_2_15
Veterans Health Administration National Drug File VANDF VANDF_2021_01_31

The following sources have not been updated since the previous RxNorm release:

Source NameSABVersion
Anatomical Therapeutic Chemical Classification System ATC ATC_2021
Medical Subject Headings (MeSH) MSH MSH2022_2021_07_20
CMS Formulary Reference File MTHCMSFRF MTHCMSFRF_2020

*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact:

RxNorm Data Changes

Pfizer-BioNTech COVID-19 Vaccine (also known as COMIRNATY) Added

The Pfizer-BioNTech COVID-19 vaccine received U.S. Food and Drug Administration (FDA) approval on August 23, 2021, for individuals ages 16 years and older. Once vaccines are approved by the FDA, companies can market the vaccines under brand names. COMIRNATY is the brand name for the Pfizer-BioNTech COVID-19 vaccine.

The FDA-authorized Pfizer-BioNTech COVID-19 vaccine for individuals ages 16 years and older will be marketed as COMIRNATY towards the end of March 2022. No change was made to the vaccine’s formula with the name change. Pfizer-BioNTech COVID-19 vaccine (also known as COMIRNATY) overview and safety information is available from the U.S. Centers for Disease Control and Prevention.

Here is the new COMIRNATY product concept in RxNorm:

2593847SBDSARS-CoV-2 (COVID-19) vaccine, mRNA-BNT162b2 0.1 MG/ML Injectable Suspension [Comirnaty]

Data Counts

Term Type or AttributeNumber
Active GPCKs452
Active BPCKs527
Active SCDs17121
Active SBDs9444
Active RXNORM MINs3769
Active RXNORM INs13739
Active RXNORM PINs3253
Active RXNORM BNs5106
Active RXNORM DFs121
Obsolete GPCKs248
Obsolete BPCKs215
Obsolete SCDs18643
Obsolete SBDs11101
Obsolete RXNORM MINs0
Obsolete RXNORM INs0
Obsolete RXNORM PINs0
Obsolete RXNORM BNs6260
Obsolete RXNORM DFs63
Editor-suppressed SCDs1874
Editor-suppressed SBDs1542
Distinct SAB=RXNORM NDCs239180

Last Reviewed: March 7, 2022