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RxNorm Release Notes

May Release - 05/02/2022

For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.


The following sources with version names in bold have been updated since the previous RxNorm release:

Source NameSABVersion
Vaccines Administered CVX CVX_2022_04_14
DrugBank DRUGBANK DRUGBANK5.0_2022_04_01
Gold Standard Drug Database GS GS_2022_04_07
Multum MediSource Lexicon MMSL MMSL_2022_04_01
Micromedex RED BOOK MMX MMX_2022_04_04
FDA Structured Product Labels MTHSPL MTHSPL_2022_04_21
FDB MedKnowledge (formerly NDDF Plus) NDDF NDDF_2022_04_13
RxNorm normalized names and codes RXNORM RXNORM_20AA_220502F
Veterans Health Administration National Drug File VANDF VANDF_2022_03_31

The following sources have not been updated since the previous RxNorm release:

Source NameSABVersion
Anatomical Therapeutic Chemical Classification System ATC ATC_2022
Medical Subject Headings (MeSH) MSH MSH2022_2021_07_20
CMS Formulary Reference File MTHCMSFRF MTHCMSFRF_2020
US Edition of SNOMED CT (drug information) SNOMEDCT_US SNOMEDCT_US_2022_01_31
USP Compendial Nomenclature USP USP_2022_2_15

*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact:

RxNorm Data Changes

Moderna COVID-19 Second Booster Vaccine Added

The U.S. Food Drug Administration (FDA) recently authorized a second booster dose of the Moderna COVID-19. Get more information about the second booster dose of COVID-19 vaccines from the FDA.

Here is the new Moderna COVID-19 second booster vaccine concept in RxNorm:

2598700SCDSARS-CoV-2 (COVID-19) vaccine, mRNA-1273 0.1 MG/ML Injectable Suspension

Data Counts

Term Type or AttributeNumber
Active GPCKs460
Active BPCKs536
Active SCDs17150
Active SBDs9447
Active RXNORM MINs3770
Active RXNORM INs13765
Active RXNORM PINs3264
Active RXNORM BNs5092
Active RXNORM DFs121
Obsolete GPCKs249
Obsolete BPCKs217
Obsolete SCDs18680
Obsolete SBDs11148
Obsolete RXNORM MINs0
Obsolete RXNORM INs0
Obsolete RXNORM PINs0
Obsolete RXNORM BNs6293
Obsolete RXNORM DFs63
Editor-suppressed SCDs1885
Editor-suppressed SBDs1553
Distinct SAB=RXNORM NDCs241948

Last Reviewed: May 2, 2022