June Release - 06/06/2022
For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.
Sources
The following sources with version names in bold have been updated since the previous RxNorm release:
| Source Name | SAB | Version |
|---|---|---|
| DrugBank | DRUGBANK | DRUGBANK5.0_2022_05_05 |
| Gold Standard Drug Database | GS | GS_2022_05_11 |
| Multum MediSource Lexicon | MMSL | MMSL_2022_05_01 |
| Micromedex RED BOOK | MMX | MMX_2022_05_09 |
| FDA Structured Product Labels | MTHSPL | MTHSPL_2022_05_26 |
| FDB MedKnowledge (formerly NDDF Plus) | NDDF | NDDF_2022_05_11 |
| RxNorm normalized names and codes | RXNORM | RXNORM_20AA_220606F |
| Veterans Health Administration National Drug File | VANDF | VANDF_2022_04_29 |
The following sources have not been updated since the previous RxNorm release:
| Source Name | SAB | Version |
|---|---|---|
| Anatomical Therapeutic Chemical Classification System | ATC | ATC_2022 |
| Vaccines Administered | CVX | CVX_2022_04_14 |
| Medical Subject Headings (MeSH) | MSH | MSH2022_2021_07_20 |
| CMS Formulary Reference File | MTHCMSFRF | MTHCMSFRF_2020 |
| US Edition of SNOMED CT (drug information) | SNOMEDCT_US | SNOMEDCT_US_2022_01_31 |
| USP Compendial Nomenclature | USP | USP_2022_2_15 |
*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact: medispan-support@wolterskluwer.com.
RxNorm Data Changes
Sotrovimab Status Change
The U.S. Food and Drug Administration determined that sotrovimab is no longer authorized to treat COVID-19 in any U.S. region earlier this year. The RxNorm data reflects this by the lack of both the Attribute Name (ATN) “RXN_HUMAN_DRUG” and a corresponding Attribute Value (ATV) for RxNorm Concept Unique Identifier (RXCUI) 2550903 with string “8 ML sotrovimab 62.5 MG/ML Injection”. The RxNorm terminology (SAB=RXNORM) National Drug Code is also absent, and the “(EUA)” in the Prescribable Name (PSN) has been deleted.
Get more information about sotrovimab from the FDA:
New Spikevax COVID-19 Vaccine Concept Added
The Moderna COVID-19 vaccine will be marketed as Spikevax. To reflect this change, a Semantic Branded Drug (SBD) concept for Spikevax will be in the RxNorm June monthly release.
Here is the new Spikevax COVID-19 vaccine concept in RxNorm:
| RXCUI | Term Type (TTY) | STRING |
|---|---|---|
| 2601552 | SBD | SARS-CoV-2 (COVID-19) vaccine, mRNA-1273 0.2 MG/ML Injectable Suspension [Spikevax] |
Get more information about Spikevax from the FDA:
Data Counts
| Term Type or Attribute | Number |
|---|---|
| Active GPCKs | 463 |
| Active BPCKs | 536 |
| Active SCDs | 17158 |
| Active SBDs | 9464 |
| Active RXNORM MINs | 3773 |
| Active RXNORM INs | 13788 |
| Active RXNORM PINs | 3268 |
| Active RXNORM BNs | 5101 |
| Active RXNORM DFs | 121 |
| Obsolete GPCKs | 249 |
| Obsolete BPCKs | 218 |
| Obsolete SCDs | 18715 |
| Obsolete SBDs | 11154 |
| Obsolete RXNORM MINs | 0 |
| Obsolete RXNORM INs | 0 |
| Obsolete RXNORM PINs | 0 |
| Obsolete RXNORM BNs | 6292 |
| Obsolete RXNORM DFs | 63 |
| Editor-suppressed SCDs | 1892 |
| Editor-suppressed SBDs | 1561 |
| SAB=RXNORM NDCs | 242798 |
| Distinct SAB=RXNORM NDCs | 242798 |
Last Reviewed: June 6, 2022