September Release - 09/06/2022
For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.
Sources
The following sources with version names in bold have been updated since the previous RxNorm release:
| Source Name | SAB | Version |
|---|---|---|
| DrugBank | DRUGBANK | DRUGBANK5.0_2022_08_01 |
| Gold Standard Drug Database | GS | GS_2022_08_05 |
| Multum MediSource Lexicon | MMSL | MMSL_2022_08_01 |
| Micromedex RED BOOK | MMX | MMX_2022_08_08 |
| FDA Structured Product Labels | MTHSPL | MTHSPL_2022_08_26 |
| FDB MedKnowledge (formerly NDDF Plus) | NDDF | NDDF_2022_08_10 |
| RxNorm normalized names and codes | RXNORM | RXNORM_20AA_220906F |
| US Edition of SNOMED CT (drug information) | SNOMEDCT_US | SNOMEDCT_US_2022_07_31 |
| USP Compendial Nomenclature | USP | USP_2022_8_12 |
| Veterans Health Administration National Drug File | VANDF | VANDF_2022_07_29 |
The following sources have not been updated since the previous RxNorm release:
| Source Name | SAB | Version |
|---|---|---|
| Anatomical Therapeutic Chemical Classification System | ATC | ATC_2022 |
| Vaccines Administered | CVX | CVX_2022_06_23 |
| Medical Subject Headings (MeSH) | MSH | MSH2022_2021_07_20 |
| CMS Formulary Reference File | MTHCMSFRF | MTHCMSFRF_2020 |
*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact: medispan-support@wolterskluwer.com.
RxNorm Data Changes
Paxlovid Pack PSN Synonyms Updated
Paxlovid is an investigational drug indicated for the treatment of certain cases of COVID-19 under a U.S. Food and Drug Administration (FDA) Emergency Use Authorization (EUA). The RxNorm team was made aware of concerns regarding dosing errors related to Paxlovid. One discussion of possible errors can be found here: Numerous Wrong Dose Errors with PAXLOVID.
RxNorm Prescribable Name (PSN) synonyms for Paxlovid brand name and generic packs were updated to help clearly identify to prescribers which pack is being prescribed. For example, one of the Paxlovid brand name pack PSNs now includes the word “Renal”.
Here are the previous PSNs for Paxlovid-related brand name and generic pack concepts in the RxNorm terminology:
| RXCUI | Term Type (TTY) |
STR |
|---|---|---|
| 2587899 | PSN | PAXLOVID 300 MG / 100 MG 5-Day Pack (EUA) |
| 2599543 | PSN | PAXLOVID 150 MG /100 MG Dose Pack (EUA) |
| 2587898 | PSN | nirmatrelvir 150 MG Oral Tablet (20) / ritonavir 100 MG Oral Tablet (10) 5 Day Pack (EUA) |
| 2599542 | PSN | nirmatrelvir 150 MG Oral Tablet (10) / ritonavir 100 MG Oral Tablet (10) 150 MG /100 MG Dose Pack (EUA) |
Here are the updated PSNs for Paxlovid-related brand name and generic pack concepts in the RxNorm terminology:
| RXCUI | Term Type (TTY) |
STR |
|---|---|---|
| 2587899 | PSN | PAXLOVID 300 MG ; 100 MG 5-Day Pack (EUA) |
| 2599543 | PSN | PAXLOVID 150 MG ; 100 MG Dose Pack (EUA), Renal |
| 2587898 | PSN | nirmatrelvir 300 MG ; ritonavir 100 MG Daily Dose Pack (EUA) |
| 2599542 | PSN | nirmatrelvir 150 MG ; ritonavir 100 MG Daily Dose Pack (EUA), Renal |
Data Counts
| Term Type or Attribute | Number |
|---|---|
| Active GPCKs | 474 |
| Active BPCKs | 543 |
| Active SCDs | 17226 |
| Active SBDs | 9424 |
| Active RXNORM MINs | 3776 |
| Active RXNORM INs | 13856 |
| Active RXNORM PINs | 3295 |
| Active RXNORM BNs | 5065 |
| Active RXNORM DFs | 122 |
| Obsolete GPCKs | 252 |
| Obsolete BPCKs | 219 |
| Obsolete SCDs | 18759 |
| Obsolete SBDs | 11264 |
| Obsolete RXNORM MINs | 0 |
| Obsolete RXNORM INs | 0 |
| Obsolete RXNORM PINs | 0 |
| Obsolete RXNORM BNs | 6356 |
| Obsolete RXNORM DFs | 63 |
| Editor-suppressed SCDs | 1901 |
| Editor-suppressed SBDs | 1569 |
| SAB=RXNORM NDCs | 245331 |
| Distinct SAB=RXNORM NDCs | 245331 |
Last Reviewed: September 6, 2022