December Release - 12/05/2022
For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.
Sources
The following sources with version names in bold have been updated since the previous RxNorm release:
| Source Name | Source Abbreviation (SAB) | Version |
|---|---|---|
| DrugBank | DRUGBANK | DRUGBANK5.0_2022_11_09 |
| Gold Standard Drug Database | GS | GS_2022_11_14 |
| Multum MediSource Lexicon | MMSL | MMSL_2022_11_01 |
| Micromedex RED BOOK | MMX | MMX_2022_11_07 |
| FDA Structured Product Labels | MTHSPL | MTHSPL_2022_11_25 |
| FDB MedKnowledge (formerly NDDF Plus) | NDDF | NDDF_2022_11_09 |
| RxNorm normalized names and codes | RXNORM | RXNORM_20AA_221205F |
| USP Compendial Nomenclature | USP | USP_2022_11_18 |
| Veterans Health Administration National Drug File | VANDF | VANDF_2022_10_31 |
The following sources have not been updated since the previous RxNorm release:
| Source Name | SAB | Version |
|---|---|---|
| Anatomical Therapeutic Chemical Classification System | ATC | ATC_2022 |
| Vaccines Administered | CVX | CVX_2022_10_24 |
| Medical Subject Headings (MeSH) | MSH | MSH2023_2022_07_27 |
| CMS Formulary Reference File | MTHCMSFRF | MTHCMSFRF_2020 |
| US Edition of SNOMED CT (drug information) | SNOMEDCT_US | SNOMEDCT_US_2022_07_31 |
*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact: medispan-support@wolterskluwer.com.
RxNorm Data Changes
Divigel Products Get Separate RXCUIs
Divigel is an estrogen topical gel product available in five different doses in single-use packets. Previously, only RXCUI 723526 with the fully specified name "estradiol 0.001 MG/MG Topical Gel [Divigel]" existed in RxNorm.
However, Divigel was split into five different concepts, each representing a different dose, starting with the December 2022 monthly release. The new concepts have Quantity Factors to distinguish each dose.
Below are the previous and new concepts related to the fully specified Divigel concepts.
Previous Divigel concept:
| RXCUI | Term Type (TTY) | STR |
|---|---|---|
| 723526 | SBD | estradiol 0.001 MG/MG Topical Gel [Divigel] |
New Divigel concepts:
| RXCUI | Term Type (TTY) | STR |
|---|---|---|
| 2619678 | SBD | 250 MG estradiol 0.001 MG/MG Topical Gel [Divigel] |
| 2619680 | SBD | 500 MG estradiol 0.001 MG/MG Topical Gel [Divigel] |
| 2619682 | SBD | 750 MG estradiol 0.001 MG/MG Topical Gel [Divigel] |
| 2619684 | SBD | 1000 MG estradiol 0.001 MG/MG Topical Gel [Divigel] |
| 2619686 | SBD | 1250 MG estradiol 0.001 MG/MG Topical Gel [Divigel] |
New generic concepts related to Divigel:
| RXCUI | Term Type (TTY) | STR |
|---|---|---|
| 2619677 | SCD | 250 MG estradiol 0.001 MG/MG Topical Gel |
| 2619679 | SCD | 500 MG estradiol 0.001 MG/MG Topical Gel |
| 2619681 | SCD | 750 MG estradiol 0.001 MG/MG Topical Gel |
| 2619683 | SCD | 1000 MG estradiol 0.001 MG/MG Topical Gel |
| 2619685 | SCD | 1250 MG estradiol 0.001 MG/MG Topical Gel |
Data Counts
| Term Type or Attribute | Number |
|---|---|
| Active GPCKs | 470 |
| Active BPCKs | 535 |
| Active SCDs | 17275 |
| Active SBDs | 9418 |
| Active RXNORM MINs | 3776 |
| Active RXNORM INs | 13928 |
| Active RXNORM PINs | 3320 |
| Active RXNORM BNs | 5069 |
| Active RXNORM DFs | 122 |
| Obsolete GPCKs | 258 |
| Obsolete BPCKs | 226 |
| Obsolete SCDs | 18789 |
| Obsolete SBDs | 11317 |
| Obsolete RXNORM MINs | 0 |
| Obsolete RXNORM INs | 0 |
| Obsolete RXNORM PINs | 0 |
| Obsolete RXNORM BNs | 6235 |
| Obsolete RXNORM DFs | 63 |
| Editor-suppressed SCDs | 1916 |
| Editor-suppressed SBDs | 1582 |
| SAB=RXNORM NDCs | 246050 |
| Distinct SAB=RXNORM NDCs | 246050 |
Last Reviewed: December 5, 2022