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RxNorm Release Notes

January Release - 01/03/2023

For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.


The following sources with version names in bold have been updated since the previous RxNorm release:

Source NameSource Abbreviation (SAB)Version
Vaccines AdministeredCVXCVX_2022_12_05
Gold Standard Drug DatabaseGSGS_2022_12_09
Multum MediSource LexiconMMSLMMSL_2022_12_01
Micromedex RED BOOKMMXMMX_2022_12_05
FDA Structured Product LabelsMTHSPLMTHSPL_2022_12_26
FDB MedKnowledge (formerly NDDF Plus)NDDFNDDF_2022_12_07
RxNorm normalized names and codesRXNORMRXNORM_20AA_230103F
USP Compendial NomenclatureUSPUSP_2022_12_12
Veterans Health Administration National Drug FileVANDFVANDF_2022_11_30

The following sources have not been updated since the previous RxNorm release:

Source NameSABVersion
Anatomical Therapeutic Chemical Classification System ATC ATC_2022
Medical Subject Headings (MeSH) MSH MSH2023_2022_07_27
CMS Formulary Reference File MTHCMSFRF MTHCMSFRF_2020
US Edition of SNOMED CT (drug information) SNOMEDCT_US SNOMEDCT_US_2022_07_31

*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact:

RxNorm Data Changes

Humalog Tempo Pen with Sensor Gets Separate RXCUI 2621572

The Humalog Tempo Pen insulin product with sensor was split from RXCUI 1652640 into a separate concept with RXCUI 2621572. The new concept uses the Qualitative Distinction modifier “Sensor” to differentiate this insulin product from others. The previous concept RXCUI 1652640 still exists for appropriate insulin products without a sensor.

Here is the new RxNorm concept for Humalog Tempo Pen with sensor:

2621572 SBD Sensor 3 ML insulin lispro 100 UNT/ML Pen Injector [Humalog]

As a reminder, Qualitative Distinction modifiers allow flexibility in the RxNorm model to create new RXCUIs as needed. See the RxNorm Technical Documentation for more information about Qualitative Distinction (QD) modifiers, which were first released in the August 2016 monthly release. For each SCD or SBD with a QD, there is an associated attribute in RXNSAT with the attribute name (ATN) of 'RXN_QUALITATIVE_DISTINCTION'.

Data Counts

Term Type or AttributeNumber
Active GPCKs472
Active BPCKs535
Active SCDs17264
Active SBDs9400
Active RXNORM MINs3773
Active RXNORM INs13945
Active RXNORM PINs3324
Active RXNORM BNs5065
Active RXNORM DFs122
Obsolete GPCKs257
Obsolete BPCKs227
Obsolete SCDs18811
Obsolete SBDs11350
Obsolete RXNORM MINs0
Obsolete RXNORM INs0
Obsolete RXNORM PINs0
Obsolete RXNORM BNs6248
Obsolete RXNORM DFs63
Editor-suppressed SCDs1920
Editor-suppressed SBDs1588
Distinct SAB=RXNORM NDCs246406

Last Reviewed: January 31, 2023