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Unified Medical Language System® (UMLS®)

RxNorm Full Monthly Content Release Notes

December Release - 12/03/2018

This release of RxNorm is consistent with the 2018AB UMLS Metathesaurus release. For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm Technical Documentation.


The following sources with version names in bold have been updated since the previous RxNorm release:

Source NameSABVersion
Vaccines Administered CVX CVX_2018_10_18
DrugBank DRUGBANK DRUGBANK5.0_2018_10_31
Gold Standard Drug Database GS GS_2018_11_01
Multum MediSource Lexicon MMSL MMSL_2018_11_01
Micromedex RED BOOK MMX MMX_2018_10_29
Medical Subject Headings (MeSH) MSH MSH2019_2018_07_31
FDA Structured Product Labels MTHSPL MTHSPL_2018_11_23
FDB MedKnowledge (formerly NDDF Plus) NDDF NDDF_2018_10_31
RxNorm normalized names and codes RXNORM RXNORM_18AB_181203F
USP Compendial Nomenclature USP USP_2018_11_20
Veterans Health Administration National Drug File VANDF VANDF_2018_11_01

The following sources have not been updated since the previous RxNorm release:

Source NameSABVersion
Anatomical Therapeutic Chemical Classification System ATC ATC_2018
CMS Formulary Reference File MTHCMSFRF MTHCMSFRF_2014
Veterans Health Administration National Drug File - Reference Terminology NDFRT NDFRT_2018_02_05
US Edition of SNOMED CT (drug information) SNOMEDCT_US SNOMEDCT_US_2018_07_31

*Reminder: As of October 2017, Medi-Span data will not be included in the RxNorm or UMLS releases. If you have questions about Medi-Span, please contact:

Data Changes

SPL Biologic Substance Names
RxNorm now includes the FDA’s nonproprietary biologic substance names with 4 letter suffixes from the DailyMed Indexing file. These biologic product names are in the FDA Structured Product Labeling (MTHSPL) source terminology with the term type of SU (TTY = SU).

Here are examples of the MTHSPL biologic substances in RxNorm:


GS Ingredients
RxNorm includes a new ingredient term type (TTY = IN) from the Gold Standard Drug Database (GS) source terminology. Five GS term types will now be available: BD, CD, MTH_RXN_BD, MTH_RXN_CD, IN.

Here are examples of the GS ingredients in RxNorm:


NDF-RT Removed for 2019
REMINDER: The RxNorm December 2018 monthly release is the last release to include Veterans Health Administration’s National Drug File – Reference Terminology (NDF-RT). Beginning in 2019, RxNorm will no longer include NDF-RT. Please plan accordingly.

Medication Reference Terminology (MED-RT) replaces NDF-RT. There are no plans to include MED-RT in RxNorm; however, MED-RT is included in the UMLS Metathesaurus along with RxNorm and its source vocabularies. MED-RT is also included in several RxNorm API resources. For more information about MED-RT, see Introduction to MED-RT as the Replacement for NDF-RT.

Data Counts

Term Type or AttributeNumber
Active GPCKs390
Active BPCKs483
Active SCDs18454
Active SBDs10416
Active RXNORM MINs4004
Active RXNORM INs12111
Active RXNORM PINs2815
Active RXNORM BNs5980
Active RXNORM DFs117
Obsolete GPCKs188
Obsolete BPCKs158
Obsolete SCDs17552
Obsolete SBDs11012
Obsolete RXNORM MINs0
Obsolete RXNORM INs0
Obsolete RXNORM PINs0
Obsolete RXNORM BNs6191
Obsolete RXNORM DFs59
Editor-suppressed SCDs1706
Editor-suppressed SBDs1444
Distinct SAB=RXNORM NDCs251181

Last Reviewed: December 3, 2018